Abetis Plus Tablet 40 mg is a combination antihypertensive medication containing Olmesartan Medoxomil and Hydrochlorothiazide. This dual-action formula is designed to manage high blood pressure (hypertension) effectively. Olmesartan, an angiotensin II receptor blocker (ARB), relaxes blood vessels, while Hydrochlorothiazide, a thiazide diuretic, reduces blood volume by promoting the excretion of salt and water. The combination helps achieve better blood pressure control and reduces the risk of cardiovascular events such as stroke, heart attack, and kidney damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Abetis Plus Tablet 40 mg is indicated for:

• Treatment of hypertension in adults
• Patients requiring combination therapy for enhanced blood pressure control
• Reduction of cardiovascular risk associated with uncontrolled hypertension

It is particularly useful for patients whose blood pressure is not adequately controlled with monotherapy.

Mechanism of Action

• Olmesartan Medoxomil blocks angiotensin II type 1 (AT1) receptors, preventing vasoconstriction and lowering blood pressure through vasodilation.
• Hydrochlorothiazide promotes renal excretion of sodium and water, decreasing blood volume and further reducing blood pressure.

The complementary actions of these two agents provide sustained and effective blood pressure reduction.

Dosage and Administration

• The usual recommended dose is one tablet once daily or as prescribed by a physician.
• It may be taken with or without food.
• Swallow the tablet whole with water; do not crush or chew.
• Take at the same time each day for optimal effect.

Dosage adjustments may be necessary based on patient response, kidney function, and blood pressure readings.

Side Effects

Common side effects may include:

• Dizziness or lightheadedness
• Headache
• Increased urination
• Fatigue
• Mild gastrointestinal discomfort

Serious but less common side effects include:

• Severe hypotension
• Electrolyte imbalances (low potassium, sodium, or magnesium)
• Kidney function impairment
• Allergic reactions

Seek immediate medical attention if severe side effects occur.

Precautions and Warnings

• Regular monitoring of blood pressure, kidney function, and electrolytes is recommended.
• Use cautiously in patients with kidney or liver disease.
• Not recommended during pregnancy due to potential harm to the fetus.
• Avoid potassium supplements or salt substitutes unless advised by a doctor.
• Inform your physician about any other medications or underlying medical conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Abetis Plus Tablet 40 mg may interact with:

• Other antihypertensive medications (enhanced blood pressure-lowering effect)
• Potassium-sparing diuretics or potassium supplements
• NSAIDs (may reduce antihypertensive effect)
• Lithium (risk of toxicity)

Always inform your healthcare provider about all medicines being taken.

Storage Instructions

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.