Avlosef Capsule 500 mg contains Cephradine, a first-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It is effective against many Gram-positive and some Gram-negative organisms, making it a reliable choice for common infections affecting different parts of the body.

Cephradine works by interfering with bacterial cell wall synthesis, ultimately leading to the destruction of bacteria. It is commonly prescribed due to its proven efficacy, safety profile, and good tolerability.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Avlosef Capsule is indicated for the treatment of infections caused by susceptible bacteria, including:

• Upper respiratory tract infections such as tonsillitis, pharyngitis, and sinusitis
• Lower respiratory tract infections including bronchitis and pneumonia
• Urinary tract infections (UTIs) such as cystitis and pyelonephritis
• Skin and soft tissue infections including cellulitis, boils, and abscesses
• Ear infections (otitis media)
• Bone infections and septicemia in appropriate cases

Composition

• Active Ingredient: Cephradine
• Strength: 500 mg
• Dosage Form: Oral capsule

Mechanism of Action

Cephradine exerts its antibacterial effect by inhibiting the synthesis of the bacterial cell wall. It binds to specific penicillin-binding proteins (PBPs), preventing the formation of peptidoglycan, an essential structural component of the bacterial cell wall. This leads to weakening of the cell wall and eventual bacterial cell death.

Dosage & Administration

• Adults: সাধারণত 1–2 g daily in divided doses (every 6–12 hours)
• Severe infections: Dose may be increased based on clinical condition
• Children: Dose should be determined based on body weight (usually 25–50 mg/kg/day in divided doses)

Capsules should be taken orally with water and can be taken with or without food. Always follow the physician’s prescribed dosage and duration.

Side Effects

Avlosef Capsule is generally well tolerated, but some patients may experience:

• Nausea, vomiting, diarrhea
• Abdominal discomfort
• Skin rash or itching
• Allergic reactions (rare but serious)
• Dizziness (occasionally)

Seek immediate medical attention if signs of severe hypersensitivity occur.

Precautions & Warnings

• Use with caution in patients with known allergy to cephalosporins or penicillins
• Dose adjustment may be necessary in patients with renal impairment
• Prolonged use may lead to superinfection or resistant organisms
• Complete the full course as prescribed to avoid antibiotic resistance

Drug Interactions

• Concurrent use with nephrotoxic drugs (e.g., aminoglycosides) may increase the risk of kidney damage
• May affect results of certain laboratory tests (e.g., Coombs’ test)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Should be used only if clearly needed and prescribed by a doctor
• Lactation: Passes into breast milk in small amounts; generally considered safe
• Elderly: Dose adjustment may be required depending on renal function

Storage

• Store below 25°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.