Axicef Suspension 125 mg/5 ml contains Cefuroxime Axetil, a second-generation cephalosporin antibiotic, formulated as a palatable oral suspension for children and patients who have difficulty swallowing tablets. It is effective against a broad spectrum of Gram-positive and Gram-negative bacteria, making it suitable for respiratory, urinary, skin, and soft tissue infections in pediatric patients.

Cefuroxime Axetil is a prodrug, which is rapidly converted into its active form, cefuroxime, in the body. This ensures optimal absorption and bactericidal activity, allowing Axicef Suspension to combat infections efficiently. Its liquid form allows accurate dosing based on body weight, ensuring safety and effectiveness in children.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Cefuroxime Axetil 125 mg per 5 ml

Mechanism of Action

Cefuroxime Axetil is a broad-spectrum bactericidal antibiotic that works by:

• Inhibiting bacterial cell wall synthesis, causing bacterial cell lysis and death

• Binding to penicillin-binding proteins (PBPs), disrupting the cross-linking of peptidoglycan in the bacterial cell wall

• Targeting both Gram-positive and Gram-negative bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli, and Klebsiella species

• Being bactericidal, effectively eliminating bacterial infections rather than merely inhibiting growth

This mechanism allows Axicef Suspension to rapidly clear bacterial infections while minimizing the risk of resistance when used appropriately.

Indications

Axicef Suspension 125 mg/5 ml is indicated for the treatment of:

• Upper respiratory tract infections: pharyngitis, tonsillitis, sinusitis

• Lower respiratory tract infections: bronchitis, community-acquired pneumonia

• Urinary tract infections such as cystitis and pyelonephritis

• Skin and soft tissue infections

• Other bacterial infections caused by susceptible strains

Benefits

• Child-Friendly Formulation: Easy-to-administer oral suspension suitable for children and patients unable to swallow tablets

• Broad-Spectrum Activity: Effective against a wide range of bacteria

• Rapid Symptom Relief: Helps reduce fever, inflammation, and bacterial load quickly

• Accurate Dosing: Can be measured based on weight for pediatric use

• Bactericidal Action: Actively kills bacteria for effective infection management

• Well-Tolerated: Safe under medical supervision when taken as directed

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• The usual pediatric dose is 20–30 mg/kg/day, divided into two doses, or as prescribed by a healthcare professional

• Shake the bottle well before each use

• Measure the dose using a calibrated measuring spoon or syringe provided with the suspension

• The duration of therapy usually ranges from 7–14 days, depending on the infection type and severity

• Complete the full course even if symptoms improve, to prevent recurrence or resistance

Safety and Precautions

• Common side effects may include diarrhea, nausea, vomiting, abdominal pain, and mild rash

• Rare serious effects can include allergic reactions, severe diarrhea due to Clostridium difficile, or blood abnormalities

• Avoid in patients with known hypersensitivity to cephalosporins or penicillin

• Use caution in patients with renal impairment; dose adjustment may be required

• Pregnant or breastfeeding mothers should use Axicef Suspension only under medical guidance

• Inform the healthcare provider of all medications to avoid potential drug interactions.