Bevacimab Injection 400 mg/16 ml contains Bevacizumab, a targeted anticancer medication used in the treatment of various malignancies. It belongs to a class of drugs known as angiogenesis inhibitors, which work by preventing the formation of new blood vessels that tumors need for growth and survival.

Bevacimab is widely used in oncology for managing cancers such as Colorectal Cancer, Non-Small Cell Lung Cancer, Breast Cancer, and Ovarian Cancer. It is typically administered in combination with chemotherapy or other anticancer therapies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each vial contains:

• Bevacizumab 400 mg in 16 ml solution

This preparation is intended for intravenous infusion and must be administered by a trained healthcare professional in a clinical setting.

Mechanism of Action

Bevacizumab is a recombinant humanized monoclonal antibody that targets vascular endothelial growth factor (VEGF), a protein responsible for promoting blood vessel formation.

Its mechanism includes:

• Binding to VEGF and preventing it from interacting with its receptors
• Inhibiting the formation of new blood vessels (angiogenesis)
• Reducing blood supply to tumors
• Slowing tumor growth and metastasis

By depriving tumors of nutrients and oxygen, Bevacizumab helps control cancer progression.

Indications

Bevacimab Injection is indicated for the treatment of:

• Colorectal Cancer
• Non-Small Cell Lung Cancer
• Breast Cancer
• Ovarian Cancer
• Renal cell carcinoma
• Cervical cancer

It is usually used in combination with chemotherapy regimens depending on the cancer type and stage.

Dosage and Administration

• Administered as an intravenous infusion under medical supervision
• Dosage depends on the type of cancer, patient weight, and treatment protocol
• Infusions are typically given every 2–3 weeks
• The first infusion is given slowly to monitor for reactions, with subsequent doses administered more rapidly if tolerated

Patients should be closely monitored during and after administration.

Benefits

Bevacimab Injection offers several clinical benefits:

• Targets tumor growth through anti-angiogenic action
• Enhances the effectiveness of chemotherapy
• Slows progression of various cancers
• Helps improve survival outcomes in certain cancer types
• Provides a targeted therapy approach with specific action on tumor pathways

Possible Side Effects

Some patients may experience side effects, including:

• High blood pressure
• Protein in urine (proteinuria)
• Bleeding or delayed wound healing
• Fatigue and कमजोरी
• Gastrointestinal perforation (rare but serious)

Infusion-related reactions may also occur in some cases.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

Before using Bevacimab Injection, inform your doctor if you have:

• Uncontrolled hypertension
• Recent surgery or planned surgery
• History of bleeding disorders
• Kidney problems
• Cardiovascular disease

Use caution during pregnancy, as the drug may harm the fetus. Effective contraception is recommended during treatment.

Storage

Store under refrigerated conditions (2°C–8°C). Do not freeze or shake the vial. Keep away from light and out of reach of children.