Biganib Tablet 180 mg contains Brigatinib, a targeted anticancer medication used in the treatment of certain types of non-small cell lung cancer (NSCLC). It belongs to a class of medicines known as tyrosine kinase inhibitors (TKIs). Brigatinib is specifically indicated for patients with anaplastic lymphoma kinase (ALK)-positive metastatic NSCLC, as determined by an approved diagnostic test.

Biganib works by targeting and blocking abnormal ALK proteins that promote cancer cell growth and survival. By inhibiting this pathway, the medication helps slow tumor progression and may reduce the spread of cancer to other parts of the body.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Brigatinib 180 mg per tablet

Mechanism of Action

Brigatinib is a selective ALK inhibitor that works by:

• Blocking abnormal ALK fusion proteins

• Inhibiting tumor cell growth and proliferation

• Reducing cancer cell survival

• Slowing disease progression

It also shows activity against certain resistant ALK mutations, making it effective in patients who may not respond to earlier treatments.

Indications

Biganib Tablet 180 mg is indicated for:

• ALK-positive metastatic non-small cell lung cancer (NSCLC)

• Patients who have progressed on or are intolerant to prior ALK inhibitor therapy

• First-line treatment in appropriate ALK-positive NSCLC cases

Treatment should be initiated and supervised by an oncologist experienced in cancer management.

Dosage and Administration

Dosage should be determined by a qualified healthcare professional.

• Typically taken once daily

• Swallow the tablet whole with water

• Can be taken with or without food

• Follow the prescribed dosing schedule strictly

In many treatment protocols, therapy may start at a lower dose before increasing to 180 mg daily, depending on physician guidance. Do not adjust or discontinue without medical advice.

Benefits

• Targeted therapy for ALK-positive lung cancer

• Helps delay disease progression

• Effective against certain resistant mutations

• Convenient once-daily oral dosing

• Supports improved treatment outcomes in eligible patients

Possible Side Effects

Common side effects may include:

• Nausea or vomiting

• Diarrhea

• Fatigue

• Cough

• Headache

• Increased blood pressure

Serious side effects may include lung inflammation, liver enzyme elevation, vision disturbances, or muscle-related issues. Immediate medical attention is required if breathing difficulties or severe symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Regular monitoring of liver function, blood pressure, and lung function is recommended

• Inform your doctor about any history of lung disease or heart problems

• Avoid pregnancy during treatment; effective contraception is advised

• Inform your physician about all current medications to prevent drug interactions

Storage

• Store below 30°C

• Protect from moisture and light

• Keep out of reach of children.