Biganib Tablet 90 mg contains Brigatinib, a targeted anticancer medicine used in the treatment of anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC). It belongs to the class of tyrosine kinase inhibitors (TKIs) and is specifically designed to block abnormal proteins that drive cancer growth.

Brigatinib is prescribed for adult patients whose lung cancer tests positive for ALK gene rearrangements. It may be used as first-line therapy or in patients who have previously received other ALK inhibitors. Biganib helps slow down tumor growth, delay disease progression, and improve overall treatment outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Brigatinib 90 mg per tablet

Mechanism of Action

Brigatinib works by selectively inhibiting the activity of abnormal ALK fusion proteins found in certain lung cancer cells. Its action includes:

• Blocking ALK tyrosine kinase activity

• Preventing cancer cell proliferation

• Reducing tumor survival signals

• Acting against certain resistant ALK mutations

By targeting the root molecular cause of ALK-positive NSCLC, Biganib provides a more precise and effective treatment approach compared to conventional chemotherapy.

Indications

Biganib Tablet 90 mg is indicated for:

• ALK-positive metastatic non-small cell lung cancer

• Patients progressing after prior ALK inhibitor therapy

• Initial dosing phase before escalation to higher maintenance doses (as directed by an oncologist)

Treatment must be initiated and monitored by a qualified oncology specialist.

Dosage and Administration

The dosage should be determined by a healthcare professional based on clinical condition and treatment plan.

• Typically taken once daily

• May be used as a starting dose before increasing to 180 mg daily

• Can be taken with or without food

• Swallow whole with water

• Do not crush or chew

Do not stop or adjust the dose without consulting your physician.

Benefits

• Targeted therapy for ALK-positive lung cancer

• Helps slow tumor growth and spread

• Effective in some resistant ALK mutations

• Convenient oral once-daily administration

• May improve progression-free survival in eligible patients

Possible Side Effects

Common side effects may include:

• Nausea

• Diarrhea

• Fatigue

• Cough

• Headache

• Elevated blood pressure

Serious but less common side effects include lung inflammation (interstitial lung disease), liver function abnormalities, muscle pain, or vision disturbances. Immediate medical attention is necessary if severe breathing problems or other serious symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Regular monitoring of liver enzymes and blood pressure is recommended

• Inform your doctor if you have a history of lung or heart disease

• Avoid pregnancy during treatment; effective contraception should be used

• Inform your healthcare provider about all other medications to prevent interactions

Storage

• Store below 30°C

• Protect from light and moisture

• Keep out of reach of children.