Civox Injection 200 mg/100 ml contains Ciprofloxacin, a broad-spectrum fluoroquinolone antibiotic used for the treatment of serious bacterial infections. Administered intravenously, Civox provides rapid and effective delivery of the drug directly into the bloodstream, ensuring immediate therapeutic action against susceptible Gram-positive and Gram-negative bacteria.

This formulation is ideal for treating severe infections where oral administration is not feasible, such as complicated urinary tract infections, respiratory tract infections, skin and soft tissue infections, and intra-abdominal infections. Civox Injection is also used in cases where rapid drug action is required, such as sepsis or hospital-acquired infections.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria
• Intravenous administration ensures rapid onset of action
• Suitable for severe or complicated infections
• Effective in hospital settings for acute infections
• Helps prevent the progression of serious bacterial infections

Indications

Civox Injection 200 mg/100 ml is indicated for:

• Complicated urinary tract infections and pyelonephritis
• Lower and upper respiratory tract infections, including pneumonia and bronchitis
• Skin and soft tissue infections
• Intra-abdominal infections
• Sepsis and systemic bacterial infections
• Bone and joint infections (osteomyelitis)

Mechanism of Action

Ciprofloxacin is a fluoroquinolone antibiotic that:

• Inhibits bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication
• Prevents bacterial cell division and growth
• Exhibits bactericidal activity, leading to bacterial cell death
• Provides a rapid and sustained antibacterial effect when administered intravenously

Dosage and Administration

• Administered intravenously by a healthcare professional
• Typical dose: 200 mg diluted in 100 ml of compatible IV fluid, given over 30–60 minutes, as per physician’s prescription
• Dosage frequency and duration depend on the type and severity of infection, renal function, and patient condition
• Adjustments may be necessary for patients with renal impairment

Side Effects

Common side effects:

• Nausea, vomiting, or diarrhea
• Headache or dizziness
• Local irritation or inflammation at the injection site

Rare but serious side effects:

• Tendon rupture or tendonitis, particularly in older adults
• Peripheral neuropathy
• Allergic reactions, including rash, itching, or anaphylaxis
• Changes in liver or kidney function tests

Precautions and Warnings

• Use with caution in patients with a history of tendon disorders or kidney impairment
• Monitor for signs of hypersensitivity or severe adverse reactions
• Avoid concurrent use with drugs that prolong QT interval or interact with Ciprofloxacin
• Adequate hydration is recommended to prevent kidney-related side effects

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• Hypersensitivity to Ciprofloxacin, other fluoroquinolones, or any component of the injection
• Concomitant use with tizanidine
• Known history of tendon rupture related to fluoroquinolone therapy

Storage Instructions

• Store below 25°C in a dry place
• Protect from light
• Keep out of reach of children
• Do not use if the solution is cloudy or contains particulate matter.