Dactus Tablet 2 mg contains Glimepiride, an oral sulfonylurea antidiabetic agent designed for the management of type 2 diabetes mellitus. It is used to control high blood sugar levels in adults and adolescents over 18 years of age. Glimepiride works by stimulating insulin secretion from the pancreatic beta cells and enhancing peripheral tissue sensitivity to insulin. Dactus Tablet 2 mg is particularly effective when lifestyle measures like diet and exercise alone are insufficient, helping reduce the risk of long-term complications associated with diabetes, such as cardiovascular disease, neuropathy, and kidney problems.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Glimepiride 2 mg

• Dosage Form: Oral tablet

• Route of Administration: Oral

Mechanism of Action

Glimepiride lowers blood glucose through a dual mechanism:

1. Stimulation of insulin secretion: Glimepiride binds to sulfonylurea receptors on pancreatic beta cells, closing ATP-sensitive potassium channels. This leads to cell depolarization, calcium influx, and increased insulin release.

2. Improved insulin sensitivity: It enhances insulin-mediated glucose uptake in peripheral tissues, such as skeletal muscles, and reduces hepatic glucose production.

These combined actions help maintain both fasting and postprandial blood glucose within a healthy range, improving overall glycemic control.

Indications

Dactus Tablet 2 mg is indicated for:

• Management of type 2 diabetes mellitus in adults and adolescents above 18 years

• Patients with inadequate glycemic control despite diet and lifestyle modifications

• Use as monotherapy or in combination with other oral antidiabetic agents or insulin

• Reducing the risk of long-term complications associated with persistent hyperglycemia

Dosage and Administration

• The usual starting dose may be 1–2 mg once daily, taken with breakfast or the first main meal to reduce the risk of hypoglycemia.

• Dose adjustments can be made based on blood glucose monitoring, up to a maximum of 8 mg per day.

• Swallow the tablet with water; do not crush or chew.

• Maintain a consistent diet and exercise regimen to maximize therapeutic outcomes.

• Regular blood sugar monitoring is essential to avoid hypoglycemia and ensure optimal glycemic control.

Contraindications

Dactus Tablet 2 mg should not be used in:

• Patients with hypersensitivity to Glimepiride or other sulfonylureas

• Type 1 diabetes mellitus

• Diabetic ketoacidosis

• Severe renal or hepatic impairment

• Pregnant or breastfeeding women unless prescribed by a physician

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Risk of hypoglycemia, especially in elderly patients, those with irregular meals, or those taking other antidiabetic medications

• Use caution in patients with kidney or liver dysfunction

• Adjust doses carefully in elderly patients to prevent hypoglycemia

• Inform your physician about all other medications being taken to avoid drug interactions

Possible Side Effects

Dactus Tablet is generally well tolerated. Common side effects include:

• Hypoglycemia (low blood sugar)

• Nausea, vomiting, or abdominal discomfort

• Dizziness or headache

• Rare side effects: skin rash, liver enzyme alterations, or hematological changes

Storage

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Conclusion

Dactus Tablet 2 mg provides effective glycemic control for patients with type 2 diabetes mellitus. Its dual action of stimulating insulin release and improving insulin sensitivity makes it a reliable choice for managing blood sugar levels. Combined with proper diet, exercise, and regular monitoring, Dactus Tablet 2 mg helps reduce the risk of diabetes-related complications while maintaining a favorable safety profile under medical supervision.