Delaflox Injection 300 mg/vial contains Delafloxacin, a novel fluoroquinolone antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It is specially formulated for intravenous administration and is primarily used in the treatment of acute bacterial infections, particularly when infections are severe or oral therapy is not appropriate.

Delafloxacin is distinguished from other fluoroquinolones by its enhanced activity in acidic environments, such as infected tissues, making it highly effective against difficult-to-treat pathogens. It demonstrates strong efficacy against methicillin-resistant Staphylococcus aureus (MRSA), streptococci, and a wide range of Gram-negative organisms. Delaflox Injection is commonly used in hospital settings under close medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Delafloxacin: 300 mg per vial

Indications

Delaflox Injection 300 mg/vial is indicated for the treatment of:

• Acute bacterial skin and skin structure infections (ABSSSI)

• Infections caused by susceptible Gram-positive and Gram-negative organisms

• Complicated bacterial infections where intravenous therapy is required

• Infections caused by MRSA, Streptococcus species, and Enterobacteriaceae

• Patients who are unable to tolerate oral antibiotics or require rapid systemic therapy

Mechanism of Action

Delafloxacin exerts its antibacterial effect by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination. Inhibition of these enzymes leads to disruption of bacterial cell division and ultimately results in bacterial cell death. Its unique chemical structure allows effective activity in acidic infection sites, enhancing its clinical efficacy.

Dosage and Administration

• Route: Intravenous infusion

• Dosage: As prescribed by a registered physician

The dose and duration of therapy depend on the type and severity of infection, patient condition, and renal function. Delaflox Injection should be administered by healthcare professionals in a clinical setting.

Benefits of Delaflox Injection 300 mg/vial

• Broad-spectrum antibacterial coverage

• Effective against MRSA and resistant pathogens

• Suitable for severe infections requiring IV therapy

• Enhanced activity in acidic infected tissues

• Reliable option for hospitalized patients

Precautions and Warnings

• Use only under specialist medical supervision

• Caution is advised in patients with renal impairment

• Fluoroquinolones may be associated with tendon disorders; use with caution in elderly patients

• Not recommended for use in children, pregnant, or breastfeeding women unless clearly indicated

• Monitor for hypersensitivity reactions and gastrointestinal disturbances

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Conditions

• Store below 30°C

• Protect from light

• Keep out of reach of children

• Reconstituted solution should be used as per manufacturer’s instructions

Pharmaceutical Category

Fluoroquinolone Antibiotic.