Diproxen CR Tablet 500 mg contains Naproxen Sodium, a non-steroidal anti-inflammatory drug (NSAID) formulated in a controlled-release (CR) form. This advanced formulation allows the medication to be gradually released over an extended period, providing long-lasting pain relief and anti-inflammatory effects with fewer doses per day. It is particularly useful for managing chronic musculoskeletal conditions, arthritis, and persistent pain, where consistent therapeutic levels are required.

Naproxen Sodium works by inhibiting cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins—chemical mediators of pain, inflammation, and fever. The controlled-release mechanism ensures steady plasma concentrations, reducing peaks and troughs associated with immediate-release formulations and minimizing the risk of gastrointestinal discomfort.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Diproxen CR Tablet 500 mg is indicated for:

• Management of chronic inflammatory conditions, including osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis

• Relief of moderate to severe musculoskeletal pain, such as back pain, sprains, and strains

• Treatment of pain and inflammation associated with soft tissue injuries

• Control of persistent fever and inflammatory symptoms where prolonged NSAID therapy is appropriate

• Long-term therapy for patients requiring consistent pain management

This controlled-release formulation is intended for adult patients under medical supervision.

Dosage and Administration

• Adults: Usually, 500 mg orally once daily, preferably with food to reduce gastrointestinal irritation.

• Maximum dose: Should not exceed the total daily dose recommended by a physician, usually 1,500 mg per day, depending on patient condition and response.

• Administration: Swallow the tablet whole with water. Do not crush, chew, or break the tablet to maintain the controlled-release properties.

For chronic conditions, it is advised to use the lowest effective dose for the shortest duration necessary to minimize the risk of adverse effects.

Precautions

• Avoid use in patients with known hypersensitivity to Naproxen, aspirin, or other NSAIDs.

• Use cautiously in patients with peptic ulcer, gastrointestinal bleeding, kidney or liver impairment, or cardiovascular disorders.

• Concurrent use with other NSAIDs should be avoided unless specifically prescribed.

• Pregnant or breastfeeding women should only use Diproxen CR under strict medical supervision.

• Elderly patients are at increased risk for gastrointestinal, renal, or cardiovascular side effects and should be monitored regularly.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Diproxen CR Tablet is generally well tolerated, but some patients may experience:

• Gastrointestinal discomfort, nausea, or heartburn

• Headache or dizziness

• Mild fluid retention or edema

• Skin rash or allergic reactions (rare)

Serious side effects such as gastrointestinal bleeding, ulceration, or severe hypersensitivity are uncommon but require immediate medical attention.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children. Do not crush or split the tablet to maintain the controlled-release mechanism.

Diproxen CR Tablet 500 mg provides sustained relief from pain and inflammation, making it ideal for patients with chronic musculoskeletal or arthritic conditions requiring prolonged NSAID therapy under professional medical supervision.