Dot Tablet 40 mg contains Drotaverine Hydrochloride, a potent antispasmodic agent widely used for the relief of smooth muscle spasms in the gastrointestinal, biliary, and genitourinary systems. It is particularly effective for conditions such as abdominal pain, colic, menstrual cramps, and biliary or ureteric colic.

Drotaverine belongs to the isoquinoline derivative class and works by relaxing smooth muscles without affecting normal muscle tone, providing rapid and effective relief from pain and discomfort caused by spasms. Unlike other antispasmodics, Drotaverine does not affect blood pressure or heart rate significantly, making it well-tolerated and safe for a wide range of patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Drotaverine Hydrochloride: 40 mg per tablet

Indications

Dot Tablet 40 mg is indicated for:

• Relief of gastrointestinal smooth muscle spasms, including intestinal colic and irritable bowel syndrome

• Biliary colic and ureteric colic caused by stones or obstruction

• Menstrual cramps (dysmenorrhea) and associated abdominal discomfort

• Smooth muscle spasms in gynaecological procedures

• Adjunct therapy for pain associated with smooth muscle contraction

Mechanism of Action

Drotaverine is a phosphodiesterase-IV inhibitor, which leads to:

1. Smooth muscle relaxation: By increasing intracellular cyclic AMP (cAMP), it reduces calcium ion concentration in smooth muscles, preventing contraction.

2. Spasm relief: Provides targeted relaxation of spastic muscles without affecting skeletal or cardiac muscles.

3. Rapid onset of action: Typically provides relief within 20–30 minutes after oral administration.

This mechanism ensures effective pain relief without causing sedation or cardiovascular side effects, making it suitable for both acute and chronic spasmodic conditions.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The usual adult dose is one tablet (40 mg) 2–3 times daily, depending on the severity of spasms. Tablets should be swallowed whole with water and can be taken with or without food. Dosage adjustments may be necessary for elderly patients or individuals with hepatic impairment.

Benefits of Dot Tablet 40 mg

• Rapid and effective relief from smooth muscle spasms

• Reduces abdominal, biliary, and ureteric colic pain

• Alleviates menstrual cramps and related discomfort

• Well-tolerated with minimal side effects

• Convenient oral formulation for home or outpatient use

• Safe for use in combination with other analgesics when prescribed

Precautions and Warnings

• Use only under medical supervision

• Avoid in patients with severe liver disease or hypersensitivity to Drotaverine

• Use caution in pregnant or breastfeeding women; only under physician guidance

• Monitor for rare side effects such as headache, dizziness, or hypotension

• Do not exceed the recommended dose to prevent adverse effects

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

Antispasmodic / Smooth Muscle Relaxant.