Duratocin Injection contains Carbetocin 100 mcg/ml, a long-acting synthetic analogue of oxytocin. It is used as a uterotonic agent to prevent and control postpartum hemorrhage (PPH) following childbirth. Carbetocin acts on the uterine smooth muscles, promoting sustained contractions of the uterus and reducing excessive bleeding after delivery, especially in cesarean section cases.

This medicine is administered in hospital settings under the supervision of qualified healthcare professionals due to its potent uterotonic effects and requirement for controlled use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Duratocin Injection is indicated for:

• Prevention of postpartum hemorrhage after cesarean section
• Management of uterine atony following childbirth
• Control of excessive bleeding after delivery
• Supportive uterotonic therapy in obstetric care
• Prevention of complications associated with weak uterine contractions

It is particularly valuable in high-risk deliveries where the likelihood of postpartum bleeding is increased.

Mechanism of Action

Carbetocin is a long-acting oxytocin receptor agonist that works by acting directly on the uterus:

• Binds to oxytocin receptors in uterine smooth muscle
• Stimulates rhythmic uterine contractions
• Enhances uterine tone and firmness after delivery
• Helps compress blood vessels in the uterus, reducing bleeding
• Provides prolonged action compared to standard oxytocin

Due to its extended half-life, Carbetocin offers sustained uterine contraction with a single dose in many clinical situations.

Dosage & Administration

• Administered as a single intravenous or intramuscular injection by healthcare professionals
• Commonly used immediately after delivery of the baby (especially in cesarean section)
• Dosage and route depend on clinical protocol and physician judgment
• Should only be used in hospital or clinical settings with emergency support available
• Continuous monitoring of uterine tone and vital signs may be required

Self-administration is strictly prohibited.

Side Effects

Duratocin Injection is generally well tolerated, but some side effects may occur:

• Nausea
• Vomiting
• Abdominal or uterine pain
• Flushing or feeling of warmth
• Headache
• Dizziness
• Hypotension (low blood pressure) in rare cases
• Tachycardia or palpitations

Serious adverse effects are uncommon when used appropriately under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use only under supervision of an obstetric specialist
• Not recommended for use before delivery of the baby
• Caution in patients with cardiovascular disease
• Monitor blood pressure during administration
• Use carefully in patients with pre-existing uterine disorders
• Avoid misuse or unsupervised administration
• Inform physician of any allergies or medical history

Storage

• Store below 25°C in a cool and dry place
• Protect from light
• Do not freeze
• Keep in original packaging
• Keep out of reach of children
• Use only before expiry date.