Ephidin Injection 25 mg/5 ml contains Ephedrine Hydrochloride, a sympathomimetic agent used in emergency and clinical settings for the management of hypotension, especially during anesthesia and spinal/epidural procedures. It acts by stimulating the sympathetic nervous system, leading to increased blood pressure and improved cardiac output. This injection is used under strict medical supervision in hospital environments.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 5 ml ampoule contains:

• Ephedrine Hydrochloride 25 mg

This formulation provides rapid and effective hemodynamic support in hypotensive conditions.

Indications

Ephidin Injection is indicated for:

• Hypotension during spinal or epidural anesthesia
• Acute hypotensive episodes during surgery
• Shock states associated with low blood pressure (as adjunct therapy)
• Bronchospasm (rare use in specific clinical settings)

It is used only in emergency or controlled hospital conditions.

Pharmacological Action

Ephedrine Hydrochloride acts as both a direct and indirect sympathomimetic:

• Stimulates alpha and beta adrenergic receptors
• Increases release of norepinephrine from nerve terminals
• Causes vasoconstriction, increasing blood pressure
• Enhances cardiac output and heart rate
• Mild bronchodilator effect due to beta-2 stimulation

These combined actions help restore and maintain adequate blood pressure.

Dosage & Administration

• Administered intravenously (IV), intramuscularly (IM), or subcutaneously as directed
• Dose is strictly individualized based on patient condition and response
• Must be administered slowly under continuous monitoring
• Only to be used by trained healthcare professionals

Improper use may lead to serious cardiovascular complications.

Side Effects

Possible side effects include:

• Hypertension
• Tachycardia (rapid heart rate)
• Palpitations
• Anxiety or restlessness
• Headache
• Nausea or vomiting
• Rare arrhythmias

Immediate medical attention is required for severe reactions.

Contraindications

• Hypersensitivity to Ephedrine
• Severe hypertension
• Tachyarrhythmias
• Pheochromocytoma
• Hyperthyroidism (use with extreme caution)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Continuous blood pressure and cardiac monitoring required
• Use cautiously in patients with cardiovascular disease
• Avoid concomitant use with MAO inhibitors
• May cause central nervous system stimulation
• Use only in emergency or anesthetic settings

Use in Pregnancy & Lactation

Ephedrine should be used during pregnancy only when clearly necessary, particularly in obstetric anesthesia for hypotension management. Caution is advised during breastfeeding.

Storage

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children.