Erenzo Tablet 70 mg contains Roxadustat, a novel oral medication designed to treat anemia associated with chronic kidney disease (CKD) in adults. Roxadustat belongs to the class of hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs), which stimulate the body’s natural production of erythropoietin while enhancing iron metabolism. By promoting red blood cell formation and improving iron availability, Erenzo Tablet 70 mg helps restore hemoglobin levels, reduce fatigue, and improve overall quality of life in CKD patients.

Anemia is a frequent complication in CKD due to the reduced ability of the kidneys to produce erythropoietin, a hormone essential for red blood cell production. Symptoms such as weakness, shortness of breath, and diminished physical performance are common and can significantly affect daily life. Erenzo Tablet 70 mg provides an effective oral therapy that addresses the underlying causes of CKD-related anemia, offering a convenient alternative to injectable erythropoiesis-stimulating agents.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features and Benefits

Active Ingredient:

• Roxadustat 70 mg per tablet

Effective Anemia Management:

• Stimulates endogenous erythropoietin production

• Improves hemoglobin levels and oxygen delivery

• Enhances iron absorption and mobilization from body stores

Convenient Oral Therapy:

• Suitable for dialysis and non-dialysis CKD patients

• Oral tablet eliminates the need for frequent injections

• Supports adherence to long-term therapy

Improved Quality of Life:

• Reduces symptoms of anemia such as fatigue, weakness, and shortness of breath

• Supports daily activities and physical performance

• May lower the need for blood transfusions

How It Works

Roxadustat functions as a hypoxia-inducible factor (HIF) stabilizer, mimicking the body’s natural response to low oxygen levels. Stabilization of HIF triggers the production of erythropoietin in the kidneys and liver, stimulating red blood cell production in the bone marrow.

In addition to increasing erythropoietin, Roxadustat regulates hepcidin, a hormone that controls iron metabolism. This enhances intestinal iron absorption and mobilizes stored iron, ensuring effective hemoglobin synthesis. This dual action addresses both insufficient erythropoietin production and impaired iron utilization, which are common causes of anemia in CKD patients.

Indications

Erenzo Tablet 70 mg is indicated for:

• Treatment of anemia in adult patients with chronic kidney disease, including those on dialysis

• Management of anemia in non-dialysis CKD patients

• Patients who require an oral alternative to injectable erythropoiesis-stimulating agents

Dosage and Administration

• Take the tablet orally as prescribed by a healthcare professional.

• Typically administered three times per week or as per individualized dosing instructions.

• Swallow the tablet with water; it can be taken with or without food.

• Regular monitoring of hemoglobin, iron parameters, and other relevant laboratory values is essential for safe and effective treatment.

Do not change the dose or discontinue therapy without consulting a doctor.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Safety Information

• Inform your physician if you have a history of cardiovascular disease, hypertension, liver disease, or thromboembolic disorders.

• Common side effects include headache, nausea, diarrhea, and elevated blood pressure.

• Serious but rare adverse events may include thromboembolic events, stroke, heart failure, or severe hypertension. Seek immediate medical attention if severe symptoms develop.

• Use caution in patients with pre-existing cardiovascular risk factors.

Storage Instructions

• Store below 30°C in a cool, dry place.

• Protect from light, heat, and moisture.

• Keep out of reach of children.

Erenzo Tablet 70 mg is a safe and effective oral therapy for CKD-related anemia. Its dual mechanism of stimulating erythropoietin production and enhancing iron utilization helps restore hemoglobin levels, reduce fatigue, and improve patient well-being. This moderate-strength tablet provides a convenient alternative to injectable treatments for long-term anemia management under medical supervision.