Evania M Tablet 5 mg + 1000 mg is a combination antidiabetic medication containing Empagliflozin and Metformin Hydrochloride. It is used for the management of type 2 diabetes mellitus in patients who require dual therapy for better blood sugar control.
This combination offers a complementary mechanism to manage both fasting and post-meal glucose levels effectively.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
Each tablet contains:
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Empagliflozin 5 mg
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Metformin Hydrochloride 1000 mg
For oral administration.
Mechanism of Action
Evania M works through two distinct mechanisms:
Empagliflozin (SGLT2 inhibitor)
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Reduces glucose reabsorption in the kidneys
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Promotes urinary excretion of excess glucose
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Helps lower blood sugar independently of insulin
Metformin (Biguanide)
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Decreases glucose production in the liver
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Improves insulin sensitivity in peripheral tissues
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Reduces intestinal glucose absorption
Together, they provide comprehensive control of blood glucose levels.
Indications
Evania M Tablet is indicated for:
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Type 2 Diabetes Mellitus
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Patients inadequately controlled on monotherapy
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As part of combination therapy with diet and exercise
Dosage and Administration
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Usually taken once or twice daily with meals (to reduce gastrointestinal side effects of metformin)
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Dose should be individualized based on patient condition
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Swallow whole with water; do not crush or chew
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Not recommended for type 1 diabetes or diabetic ketoacidosis
Benefits
Evania M Tablet provides several benefits:
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Dual action improves overall glycemic control
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Reduces both fasting and postprandial glucose levels
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Helps with modest weight loss (due to empagliflozin)
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Low risk of hypoglycemia when used alone
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May offer cardiovascular benefits
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Convenient combination reduces pill burden
Possible Side Effects
Common side effects include:
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Gastrointestinal upset (nausea, diarrhea, abdominal discomfort)
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Increased urination
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Urinary tract infections
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Metallic taste (due to metformin)
Less common side effects:
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Vitamin B12 deficiency (long-term use of metformin)
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Dizziness
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Weakness
Serious side effects:
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Lactic Acidosis
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Diabetic Ketoacidosis
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Kidney impairment
Precautions
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Take with meals to reduce stomach upset
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Monitor kidney function regularly
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Avoid excessive alcohol consumption
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Use cautiously in elderly patients
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Temporarily stop before major surgery or contrast imaging procedures
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Ensure adequate hydration
Drug Interactions
Evania M may interact with:
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Diuretics (risk of dehydration)
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Insulin or sulfonylureas (risk of hypoglycemia)
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Alcohol (increases risk of lactic acidosis)
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Certain contrast agents used in imaging
Storage
Store in a cool, dry place below 30°C, away from moisture and light. Keep out of reach of children.