Furotil Plus Tablet 125 mg + 31.25 mg is a combination antibiotic containing Cefuroxime Axetil and Clavulanic Acid. This formulation is used to treat a wide range of bacterial infections by combining a broad-spectrum antibiotic with an enzyme inhibitor that prevents bacterial resistance.
The addition of clavulanic acid helps protect cefuroxime from degradation by beta-lactamase–producing bacteria, thereby increasing its effectiveness.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
Each tablet contains:
-
Cefuroxime Axetil 125 mg
-
Clavulanic Acid 31.25 mg
For oral administration.
Mechanism of Action
Cefuroxime Axetil
-
Inhibits bacterial cell wall synthesis
-
Leads to bacterial cell death (bactericidal action)
-
Effective against a broad range of Gram-positive and Gram-negative bacteria
Clavulanic Acid
-
Inhibits beta-lactamase enzymes produced by resistant bacteria
-
Prevents inactivation of cefuroxime
-
Expands the antibiotic spectrum
Together, they provide enhanced antibacterial activity against resistant organisms.
Indications
Furotil Plus Tablet is indicated for the treatment of:
-
Respiratory tract infections (e.g., bronchitis, pneumonia)
-
Ear, nose, and throat infections (e.g., sinusitis, tonsillitis)
-
Urinary tract infections
-
Skin and soft tissue infections
-
Some dental infections
Dosage and Administration
-
Dosage should be determined by a physician based on infection severity
-
Usually taken twice daily after meals
-
Tablets should be swallowed whole with water
-
Complete the full course even if symptoms improve early
Benefits
Furotil Plus Tablet offers several advantages:
-
Broad-spectrum antibacterial coverage
-
Effective against beta-lactamase–producing bacteria
-
Reduces risk of treatment failure due to resistance
-
Suitable for various common infections
-
Convenient oral dosing
Possible Side Effects
Common side effects include:
-
Nausea
-
Diarrhea
-
Abdominal discomfort
-
Headache
Less common side effects:
-
Skin rash
-
Dizziness
-
Vomiting
Serious side effects (rare):
-
Severe allergic reactions (hypersensitivity)
-
Clostridioides difficile infection
-
Liver enzyme elevation
Precautions
-
Check for allergy to cephalosporins or penicillins before use
-
Use cautiously in patients with kidney impairment
-
Maintain adequate hydration
-
Inform the doctor about any history of gastrointestinal disease
-
Avoid unnecessary use to prevent antibiotic resistance
Drug Interactions
Furotil Plus may interact with:
-
Antacids (may reduce absorption of cefuroxime)
-
Probenecid (may increase antibiotic levels)
-
Oral anticoagulants (may alter bleeding risk)
Storage
Store in a cool, dry place below 30°C, away from light and moisture. Keep out of reach of children.