Glifo-M XR Tablet 10 mg+1000 mg is a combination oral antidiabetic medicine formulated with Empagliflozin and Metformin Hydrochloride in an extended-release (XR) form. It is prescribed for the management of type 2 diabetes mellitus in adults, particularly when blood glucose levels are not adequately controlled by diet, exercise, or monotherapy.

This dual-action formula combines two well-established antidiabetic agents that work through complementary mechanisms to provide effective and sustained glycemic control throughout the day.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each extended-release tablet contains:

• Empagliflozin 10 mg

• Metformin Hydrochloride 1000 mg (Extended Release)

Mechanism of Action

Empagliflozin belongs to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by reducing glucose reabsorption in the kidneys, allowing excess glucose to be excreted through urine. This helps lower blood sugar levels independently of insulin action.

Metformin Hydrochloride is a biguanide that primarily reduces hepatic glucose production and improves insulin sensitivity. It also decreases intestinal glucose absorption and enhances peripheral glucose uptake.

The extended-release formulation of Metformin ensures gradual drug release, minimizing gastrointestinal discomfort and maintaining stable blood glucose levels.

Indications

Glifo-M XR Tablet is indicated for:

• Management of type 2 diabetes mellitus in adults

• Improvement of glycemic control alongside diet and exercise

• Patients requiring combination therapy for better blood sugar regulation

• Individuals at risk of cardiovascular complications associated with type 2 diabetes (as advised by a physician)

Benefits

• Provides dual mechanism glucose control

• Helps reduce fasting and postprandial blood glucose

• Extended-release formulation improves gastrointestinal tolerability

• May support weight management due to urinary glucose excretion

• Convenient once-daily dosing in many cases

Dosage and Administration

The dosage should be determined by a registered healthcare professional based on the patient’s medical condition and response to therapy. It is generally taken once daily with meals to reduce the risk of gastrointestinal side effects. The tablet should be swallowed whole and not crushed or chewed.

Precautions

• Not recommended for patients with severe renal impairment

• Monitor kidney function regularly during treatment

• Risk of lactic acidosis, though rare, is associated with Metformin

• Maintain adequate hydration to reduce the risk of dehydration

• Inform your doctor about any history of cardiovascular, liver, or kidney disease

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea or gastrointestinal discomfort

• Increased urination

• Urinary tract infections

• Genital fungal infections

• Headache

If any severe or persistent side effects occur, immediate medical attention is advised.

Storage

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Glifo-M XR Tablet 10 mg+1000 mg is an effective combination therapy designed to provide comprehensive blood glucose control in adults with type 2 diabetes when used under proper medical supervision.