Indapa-Plus Tablet 4 mg + 1.25 mg is a fixed-dose combination medicine containing Perindopril 4 mg and Indapamide 1.25 mg. It is primarily used for the management of hypertension (high blood pressure) in adults. This combination therapy works through two complementary mechanisms to effectively lower blood pressure and reduce the risk of cardiovascular complications.

Hypertension is a major risk factor for heart attack, stroke, heart failure, and kidney damage. Indapa-Plus Tablet helps control blood pressure levels, improving long-term cardiovascular outcomes when used as part of a comprehensive treatment plan that includes lifestyle modifications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Perindopril 4 mg (as Perindopril Erbumine or equivalent)

• Indapamide 1.25 mg

Mechanism of Action

Perindopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by relaxing and widening blood vessels, making it easier for the heart to pump blood. It reduces the production of angiotensin II, a substance that causes blood vessels to constrict. This leads to decreased blood pressure and improved blood flow.

Indapamide is a thiazide-like diuretic (water tablet). It helps the body eliminate excess salt and water through urine, reducing fluid volume and lowering blood pressure. It also has mild vasodilatory properties that contribute to its antihypertensive effect.

Together, these two components provide effective and sustained blood pressure control.

Indications

Indapa-Plus Tablet 4 mg + 1.25 mg is indicated for:

• Essential hypertension

• Patients not adequately controlled with single-agent therapy

• Reduction of cardiovascular risk in hypertensive patients

It may be prescribed alone or in combination with other antihypertensive medicines as directed by a physician.

Dosage and Administration

• The usual recommended dose is one tablet once daily, preferably in the morning.

• Take before meals, unless otherwise directed by your healthcare provider.

• Swallow the tablet whole with water.

• Follow your doctor’s instructions carefully and do not exceed the prescribed dose.

Regular blood pressure monitoring is recommended during treatment.

Precautions

Before taking Indapa-Plus Tablet, inform your doctor if you have:

• Kidney or liver disease

• Diabetes

• Electrolyte imbalance

• History of angioedema

• Heart failure

• Gout

ACE inhibitors may cause a persistent dry cough in some patients. Indapamide may alter electrolyte levels, so periodic blood tests may be required.

Use in Pregnancy and Lactation

Indapa-Plus Tablet is not recommended during pregnancy due to potential risk to the fetus. It should also be avoided during breastfeeding unless clearly advised by a physician.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Dizziness or lightheadedness

• Headache

• Dry cough

• Increased urination

• Fatigue

Serious side effects are rare but may include severe allergic reactions, electrolyte disturbances, or kidney function changes. Seek medical attention if unusual symptoms occur.

Storage

Store below 30°C in a cool, dry place away from moisture and direct light. Keep out of reach of children.

Indapa-Plus Tablet 4 mg + 1.25 mg offers a reliable dual-action approach for effective blood pressure control and long-term cardiovascular protection under medical supervision.