1. As a dietary supplement:

• Vitamin E deficiency caused by impaired absorption or low dietary intake.

• Increased requirements due to diets rich in polyunsaturated fats.

• Healthy hair and skin maintenance.

• Antioxidant support to protect cells from oxidative stress.

• Hemolytic anemia due to Vitamin E deficiency.

2. Therapeutic use:

• Cardiovascular disease management and prevention.

• Heavy metal poisoning support.

• Hepatotoxin poisoning protection.

• Hemolytic anemia treatment.

• Oxygen therapy to reduce oxidative damage.

• Nutritional deficiency states in adults and children.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Vitamin E Preparations

Pharmacology

Vitamin E (tocopherol) is a fat-soluble antioxidant that protects polyunsaturated fatty acids, vitamin A, and vitamin C from oxidative damage. Its effects are particularly important in maintaining cell membrane integrity and preventing free radical-induced cellular injury.

• In neonates: Deficiency may lead to irritability, edema, thrombosis, and hemolytic anemia.

• In adults and children: Low tocopherol levels can cause creatinuria, ceroid deposition, muscle weakness, decreased erythrocyte survival, and increased susceptibility to oxidative hemolysis.

Dosage & Administration

• Cardiovascular health: 400–800 IU/day

• Deficiency in adults: 200–400 IU/day

• Deficiency in children: 200 IU/day

• Thalassemia: 800 IU/day

• Sickle-cell anemia: 400 IU/day

• Skin & hair improvement: 200–400 IU/day (topical use also applicable)

• Chronic cold in adults: 200 IU/day

Administration: Oral, with meals to improve absorption; topical application for skin/hair benefits.

Interactions

• May impair Vitamin A absorption.

• Can affect Vitamin K function.

• Potentiates the effect of Warfarin, increasing bleeding risk.

Contraindications

• No specific contraindications reported.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

• Usually safe at recommended doses.

• Overdose (>1 g/day) may cause:

  • Hypertension

  • Fatigue

  • Diarrhea

  • Myopathy

Pregnancy & Lactation

• Safe when used at recommended doses.

• High doses are not established as safe.

Precautions & Warnings

• May increase risk of thrombosis in patients taking estrogen therapy.

• Monitor dosage in combination with anticoagulants (e.g., Warfarin).

Storage Conditions

• Store in a cool, dry place, away from light and heat.

• Keep out of reach of children.

Use in Special Populations

• Safe for children at recommended doses.

• Suitable for adults and elderly for antioxidant and therapeutic purposes.