Intobac 300 mg/5 ml is a topical ophthalmic antibiotic formulated to treat bacterial infections of the eye and its adnexa. It is effective against susceptible bacterial strains and works by disrupting bacterial protein synthesis, thereby eliminating infection. Available as both eye drops and ointment, Intobac 300 mg/5 ml is suitable for mild to severe external eye infections, providing targeted antibacterial therapy under professional supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Ophthalmic antibacterial drugs

Composition

Each 5 ml contains:

• Tobramycin 300 mg

Indications

Intobac 300 mg/5 ml is indicated for the treatment of:

• External bacterial infections of the eye, such as conjunctivitis

• Infections of the ocular adnexa, including eyelid and periocular infections

Treatment should be accompanied by monitoring to ensure bacterial susceptibility and therapeutic response.

Pharmacology

Intobac 300 mg/5 ml is an aminoglycoside antibiotic that inhibits bacterial protein synthesis. It binds to the 30S and 50S ribosomal subunits, leading to defective bacterial cell membranes and bacterial death. Its localized action provides effective treatment for external ocular infections with minimal systemic absorption.

Dosage and Administration

Eye Drops:

• Mild to moderate infections: 1 drop into the affected eye(s) every 4 hours

• Severe infections: 1 drop hourly until improvement, then taper dosage before discontinuation

Eye Ointment:

• Mild to moderate infections: Apply thinly into the conjunctival sac 2–3 times per day

• Severe infections: Apply thinly 3–4 times per day until improvement, then taper dosage

Proper hygiene and adherence to dosing schedules are essential for effective treatment.

Contraindications

• Known hypersensitivity to Tobramycin or other components of the formulation

• Cross-reactivity with other aminoglycosides may occur

Side Effects

• Localized ocular reactions such as:

  • Lid itching and swelling

  • Conjunctival erythema

• Side effects are rare, occurring in less than 3% of patients treated

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Specific interactions with other drugs have not been established for ophthalmic use

• Exercise caution when combining with other topical eye medications

Precautions and Warnings

• Prolonged use may result in overgrowth of non-susceptible organisms, including fungi

• Discontinue treatment if super-infection occurs and initiate alternative therapy

• Avoid touching the dropper or ointment tip to any surface to maintain sterility

• Do not wear contact lenses during treatment unless directed by a physician; wait at least 15 minutes after application before reinsertion

• Use caution when driving or operating machinery, as blurred vision may occur

• Avoid concurrent use of other eye medications unless prescribed

Pregnancy and Lactation

• Pregnancy: Use only if clearly necessary

• Lactation: Exercise caution; weigh the benefits of therapy against potential risks to the nursing infant

Storage Conditions

• Store in a cool, dry place, protected from light

• Keep out of reach of children.