Laxopride Tablet 1 mg (Prucalopride Succinate)

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Laxopride Tablet 1 mg contains Prucalopride Succinate, a selective serotonin (5-HT4) receptor agonist used in the management of chronic constipation. It is designed to improve bowel movement frequency by enhancing natural colonic motility in patients who have an inadequate response to conventional laxatives.

This lower-strength formulation is suitable for patients who require a gradual or adjusted dosing approach based on clinical condition and physician recommendation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

  • Active Ingredient: Prucalopride Succinate
  • Strength: 1 mg
  • Dosage Form: Oral tablet

Mechanism of Action

Prucalopride selectively stimulates 5-HT4 receptors in the gastrointestinal tract, which leads to:

  • Increased colonic peristalsis
  • Improved intestinal transit time
  • Enhanced spontaneous bowel movements
  • Restoration of normal bowel rhythm

Unlike stimulant laxatives, it acts through a receptor-mediated mechanism, supporting more physiological bowel function.


Indications

Laxopride Tablet 1 mg is indicated for:

  • Chronic idiopathic constipation
  • Constipation not adequately controlled with standard laxatives
  • Functional bowel motility disorders
  • Patients requiring lower or adjusted dosing therapy

Dosage and Administration

  • Usual dose: 1 mg once daily, or as prescribed by a physician
  • Can be taken with or without food
  • Swallow whole with water
  • Dose may be adjusted based on response and tolerability
  • Regular follow-up is recommended during therapy

Benefits

  • Improves natural bowel movement frequency
  • Suitable for individualized dose titration
  • Non-habit forming when used appropriately
  • Enhances intestinal motility through targeted action
  • Helps restore regular bowel function in chronic constipation
  • May be preferred for patients sensitive to higher doses

Side Effects

Common side effects may include:

  • Headache
  • Nausea
  • Abdominal pain
  • Diarrhea
  • Dizziness

Less common or rare effects:

  • Mood changes (rare)
  • Hypersensitivity reactions
  • Persistent gastrointestinal discomfort

Medical attention should be sought if severe symptoms occur.


Precautions and Warnings

  • Use strictly under medical supervision
  • Not recommended in intestinal obstruction or perforation
  • Caution in patients with severe renal impairment
  • Monitor patients with history of depression or psychiatric conditions
  • Avoid unsupervised long-term use
  • Maintain adequate hydration and dietary fiber intake

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

  • Pregnancy: Use only if clearly necessary and prescribed
  • Lactation: Not recommended unless advised by a physician
  • Elderly: May require careful monitoring
  • Pediatric use: Not routinely recommended without specialist advice

Storage

  • Store below 25°C
  • Protect from moisture and direct sunlight
  • Keep tightly closed in original packaging
  • Keep out of reach of children.

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Laxopride Tablet 1 mg (Prucalopride Succinate)
Laxopride Tablet 1 mg (Prucalopride Succinate)
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