Lefabac Injection 150 mg/15 ml contains Lefamulin Acetate, a novel pleuromutilin-class antibiotic formulated for intravenous (IV) administration. It is primarily indicated for the treatment of community-acquired bacterial pneumonia (CABP) and other serious bacterial infections in adults who require hospital-based therapy. Lefamulin works by selectively binding to the 50S ribosomal subunit, inhibiting bacterial protein synthesis, and effectively halting bacterial growth.

The injection formulation allows rapid, controlled delivery of the active compound directly into the bloodstream, ensuring quick therapeutic levels. Lefabac Injection is especially useful in patients who cannot take oral medications, those with severe infections, or during the initial treatment phase before transitioning to oral therapy. It demonstrates broad-spectrum antibacterial activity, particularly against Gram-positive pathogens like Streptococcus pneumoniae, and atypical respiratory pathogens such as Mycoplasma pneumoniae and Chlamydophila pneumoniae. Its unique mechanism also reduces the risk of cross-resistance with other antibiotic classes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Rapid and effective treatment: Achieves therapeutic plasma levels quickly for faster recovery.
• Broad-spectrum activity: Effective against Gram-positive and atypical respiratory pathogens.
• Novel mechanism of action: Low risk of cross-resistance with other antibiotics.
• Hospital-based therapy: Ideal for severe infections or patients unable to take oral medications.
• Transition therapy: Can be used initially before switching to oral Lefabac tablets for outpatient care.

Indications

• Community-acquired bacterial pneumonia (CABP) in adults
• Severe infections caused by susceptible Gram-positive and atypical pathogens
• Alternative therapy in cases of resistance or intolerance to other antibiotics, as prescribed

Dosage and Administration

• Adults: Typically 150 mg intravenously every 12 hours over 60 minutes, as recommended by the physician.
• Administer via slow IV infusion to reduce the risk of local irritation or adverse reactions.
• Dosage adjustments may be necessary in patients with severe hepatic impairment.
• Complete the full course of therapy even if symptoms improve to prevent relapse or resistance.

Precautions

• Not recommended for patients with hypersensitivity to pleuromutilins.
• Use cautiously in patients with severe liver disease.
• Monitor for infusion-related reactions and gastrointestinal side effects.
• Inform the physician about all current medications to avoid potential drug interactions.
• Pregnancy and breastfeeding: Use only under strict medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

• Nausea, vomiting, or diarrhea
• Headache or dizziness
• Rare: liver enzyme elevation or hypersensitivity reactions
• Infusion site reactions such as redness or mild pain

Storage

• Store in a cool, dry place below 25°C and protect from light.
• Do not freeze.
• Keep out of reach of children.
• Use the solution immediately after opening or reconstitution as instructed.

Lefabac Injection 150 mg/15 ml provides fast, reliable, and hospital-ready therapy for serious bacterial infections. Its intravenous delivery ensures rapid action, broad-spectrum coverage, and supports smooth transition to oral therapy for continued recovery.