Lenva Capsule 4 mg contains Lenvatinib Mesylate, an oral anticancer medication belonging to the class of tyrosine kinase inhibitors (TKIs). It is used in the treatment of certain advanced cancers by blocking tumor growth and reducing the formation of new blood vessels that supply cancer cells. Lenva is commonly used in thyroid cancer, liver cancer, and renal cell carcinoma under specialist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Lenvatinib Mesylate equivalent to Lenvatinib 4 mg

Mechanism of Action

Lenvatinib works by inhibiting multiple receptor tyrosine kinases involved in tumor growth and angiogenesis, including VEGFR, FGFR, PDGFR, KIT, and RET pathways. By blocking these signaling pathways, it reduces tumor blood supply, inhibits cancer cell proliferation, and slows disease progression.

Indications

Lenva Capsule 4 mg is indicated for:

• Differentiated thyroid cancer (radioiodine-refractory)
• Advanced renal cell carcinoma
• Hepatocellular carcinoma (liver cancer)
• Endometrial carcinoma (in combination therapy in selected cases)

Dosage and Administration

• Taken orally once daily, with or without food.
• Swallow capsules whole with water; do not crush or open.
• Dosage is individualized based on body weight, disease type, and tolerance.
• Must be taken exactly as prescribed by an oncologist.
• Regular monitoring is essential during treatment.

Benefits

• Targets multiple cancer growth pathways
• Helps slow tumor progression and spread
• Improves progression-free survival in several cancers
• Oral administration provides convenience compared to injectable therapies
• Effective in advanced and difficult-to-treat cancers

Side Effects

Common side effects may include:

• High blood pressure (hypertension)
• Fatigue and weakness
• Decreased appetite and weight loss
• Diarrhea
• Nausea

Serious side effects may include:

• Liver toxicity
• Kidney problems
• Protein in urine (proteinuria)
• Bleeding or clotting disorders
• Heart-related complications

Immediate medical attention is required if severe symptoms occur.

Precautions and Warnings

• Blood pressure should be monitored regularly during treatment.
• Liver and kidney function tests are required periodically.
• Not recommended during pregnancy due to risk of fetal harm.
• Use with caution in patients with heart disease or bleeding disorders.
• Wound healing may be affected; inform the doctor before surgery.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Lenva may interact with:

• Strong CYP3A4 inhibitors or inducers
• Antihypertensive medications
• Anticoagulants

Always inform your doctor about all medicines and supplements being used.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.