Lexel Tablet 2.5 mg contains Letrozole, a non-steroidal aromatase inhibitor used primarily in the treatment of hormone receptor–positive breast cancer in postmenopausal women. It works by reducing estrogen production in the body, thereby slowing or stopping the growth of estrogen-dependent cancer cells. It is also used in certain infertility treatments under specialist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Letrozole 2.5 mg

Mechanism of Action

Letrozole inhibits the aromatase enzyme, which is responsible for converting androgens into estrogen in peripheral tissues. By significantly lowering estrogen levels, it deprives hormone-sensitive breast cancer cells of the hormones they need to grow and multiply, helping to control disease progression.

Indications

Lexel Tablet 2.5 mg is indicated for:

• Hormone receptor-positive breast cancer in postmenopausal women
• Advanced or metastatic breast cancer
• Adjuvant therapy following surgery in breast cancer patients
• Ovulation induction in selected infertility cases (off-label use under medical supervision)

Dosage and Administration

• Usually taken once daily, with or without food
• Swallow the tablet whole with water
• Dosage depends on the condition being treated and physician recommendation
• In breast cancer treatment, therapy is often long-term
• Strict adherence to prescribed dosage is important for effectiveness

Benefits

• Reduces estrogen levels effectively in postmenopausal women
• Helps slow or stop the growth of hormone-sensitive breast cancer
• Can be used as part of long-term cancer management
• Oral administration improves patient convenience
• Also used in fertility treatment protocols under specialist care

Side Effects

Common side effects may include:

• Hot flashes
• Fatigue
• Joint and muscle pain
• Headache
• Nausea

Serious side effects:

• Bone thinning (osteoporosis)
• Increased cholesterol levels
• Vaginal dryness or bleeding
• Liver function abnormalities (rare)

Medical attention should be sought if severe symptoms occur.

Precautions and Warnings

• Not for use in premenopausal women unless specifically advised
• Bone density monitoring is recommended during long-term use
• Use cautiously in patients with liver or bone disorders
• Not recommended during pregnancy or breastfeeding
• Regular medical follow-up is required during therapy

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Lexel Tablet may interact with:

• Estrogen-containing medications
• Tamoxifen (may reduce effectiveness if used together)
• Certain hormonal therapies

Always inform your doctor about all medications being used.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.