Liptor Tablet 20 mg contains Atorvastatin Calcium, a widely prescribed statin used to manage high cholesterol and prevent cardiovascular disease. It works by inhibiting HMG-CoA reductase, a key enzyme in cholesterol biosynthesis in the liver. By reducing cholesterol production, Liptor lowers low-density lipoprotein (LDL) and total cholesterol while modestly increasing high-density lipoprotein (HDL) levels and reducing triglycerides.

Liptor 20 mg is indicated for adults with hypercholesterolemia, mixed dyslipidemia, and other lipid disorders. It is particularly beneficial for patients with a high risk of cardiovascular events, including those with diabetes, hypertension, or a history of heart disease. By improving lipid profiles, Liptor helps reduce the risk of heart attack, stroke, and atherosclerosis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

HMG-CoA Reductase Inhibitor (Statin)

Indications

Liptor Tablet 20 mg is indicated for:

• Primary hypercholesterolemia (Type IIa) and mixed dyslipidemia (Type IIb)

• Familial hypercholesterolemia (heterozygous) as adjunct to diet and lifestyle changes

• Hypertriglyceridemia to reduce elevated triglyceride levels

• Prevention of cardiovascular disease in patients with risk factors such as diabetes, hypertension, or a history of coronary heart disease

• Atherosclerotic plaque stabilization to slow progression of coronary artery disease

It is recommended that therapy be combined with a cholesterol-lowering diet, exercise, and lifestyle modifications for optimal results.

Pharmacology

Mechanism of Action:

• Atorvastatin inhibits HMG-CoA reductase, reducing hepatic cholesterol synthesis

• Lowers plasma LDL and total cholesterol levels

• Reduces triglycerides and increases HDL cholesterol moderately

• Improves endothelial function and stabilizes atherosclerotic plaques

• Reduces inflammation and oxidative stress in blood vessels, providing cardiovascular protection

Clinical Benefits:

• Significant reduction in LDL cholesterol levels

• Lowered total cholesterol and triglycerides

• Improved HDL cholesterol levels

• Decreased risk of cardiovascular events, including myocardial infarction and stroke

Dosage and Administration

• Adults: 10–80 mg once daily, usually starting at 10–20 mg

• Take with or without food, preferably at the same time each day

• Dose should be individualized based on lipid levels, therapeutic response, and tolerability

• Monitor lipid profiles and liver function tests regularly

• Lifestyle modifications (diet, exercise, weight control) should continue during therapy

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Monitor liver function tests prior to initiation and periodically during treatment

• Use caution in patients with liver disease or heavy alcohol consumption

• Report muscle pain, tenderness, or weakness, which may indicate myopathy

• Avoid concurrent use of strong CYP3A4 inhibitors unless under strict supervision

Possible Side Effects

• Common: headache, dyspepsia, abdominal pain, nausea

• Musculoskeletal: myalgia, mild muscle weakness

• Rare: myopathy, rhabdomyolysis

• Liver enzyme elevation may occur; monitor regularly

Contraindications

• Hypersensitivity to atorvastatin or any component of the formulation

• Active liver disease or unexplained persistent elevations of liver enzymes

• Pregnancy and breastfeeding

• Co-administration with certain drugs that significantly increase risk of myopathy

Pregnancy & Lactation

• Pregnancy Category X: contraindicated due to potential fetal harm

• Not recommended during breastfeeding

Storage

Store in a cool, dry place below 30°C, away from light and moisture. Keep out of reach of children.