Lizorex Injection 2 mg/ml contains Linezolid, a potent antibiotic from the oxazolidinone class, used for the treatment of serious bacterial infections caused by Gram-positive organisms, including drug-resistant strains. It is commonly administered in hospital settings for patients who require intravenous therapy, especially in severe infections where oral treatment is not suitable.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Linezolid 2 mg/ml

Mechanism of Action

Linezolid works by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit and prevents the formation of the initiation complex necessary for protein production. This action effectively stops bacterial growth and helps eliminate infection, particularly in resistant Gram-positive bacteria.

Indications

Lizorex Injection is indicated for:

• Hospital-acquired pneumonia
• Community-acquired pneumonia
• Complicated skin and soft tissue infections
• Infections caused by MRSA
• Infections caused by VRE
• Other severe Gram-positive bacterial infections requiring IV therapy

Dosage and Administration

• Administered via intravenous infusion under medical supervision
• Usual adult dose: 600 mg every 12 hours (or as prescribed)
• Infusion should be given over 30 to 120 minutes
• Dosage may vary based on patient condition and severity of infection
• Can be switched to oral therapy when clinically appropriate

Benefits

• Highly effective against multi-drug resistant Gram-positive bacteria
• Suitable for severe infections requiring intravenous treatment
• Enables step-down therapy to oral form once condition improves
• High bioavailability ensures consistent therapeutic effect
• Widely used in hospital and critical care settings

Side Effects

Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Headache
• Injection site reactions

Serious side effects may include:

• Bone marrow suppression (anemia, thrombocytopenia)
• Peripheral and optic neuropathy (with prolonged use)
• Lactic acidosis (rare but serious)
• Serotonin syndrome when used with certain medications

Immediate medical attention is required if serious symptoms occur.

Precautions and Warnings

• Regular monitoring of complete blood count (CBC) is necessary
• Use cautiously in patients with liver or kidney impairment
• Avoid prolonged use to reduce risk of nerve damage
• Monitor for signs of serotonin syndrome when combined with antidepressants
• Should be used only under strict medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Lizorex Injection may interact with:

• SSRIs, SNRIs, and MAO inhibitors
• Sympathomimetic agents
• Other antibiotics

Always inform the healthcare provider about all medications being used.

Storage

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children.