Metarin Tablet 850 mg contains Metformin Hydrochloride, an oral antidiabetic medicine widely used as first-line therapy for type 2 diabetes mellitus. It helps control high blood sugar levels by improving the body’s response to insulin and reducing glucose production in the liver.

This higher-strength formulation is commonly prescribed when better glycemic control is required with once or twice daily dosing.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Metformin Hydrochloride
• Strength: 850 mg
• Dosage Form: Oral tablet

Mechanism of Action

Metformin lowers blood glucose through multiple actions:

• Reduces hepatic glucose production (gluconeogenesis)
• Increases peripheral insulin sensitivity
• Enhances glucose uptake in muscle tissues
• Decreases intestinal absorption of glucose

It does not stimulate insulin secretion, which helps minimize the risk of hypoglycemia when used alone.

Indications

Metarin Tablet 850 mg is indicated for:

• Type 2 diabetes mellitus
• Insulin resistance
• Polycystic ovary syndrome (PCOS) (as prescribed)
• Adjunct therapy in metabolic syndrome

Dosage and Administration

• Use only as directed by a physician
• Usually taken with meals to reduce gastrointestinal discomfort
• Dosage is individualized based on blood glucose levels
• Swallow whole with water
• Regular monitoring of blood sugar and kidney function is recommended

Benefits

• Effectively lowers fasting and post-meal blood sugar levels
• Improves insulin sensitivity
• Helps reduce long-term diabetes complications
• Does not typically cause weight gain
• Well-established first-line therapy for type 2 diabetes
• Suitable for long-term use under supervision

Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Metallic taste
• Loss of appetite

Less common but serious effects:

• Lactic acidosis (rare but serious)
• Vitamin B12 deficiency with long-term use
• Hypoglycemia (rare when used alone)

Precautions and Warnings

• Use only under medical supervision
• Monitor kidney function regularly
• Avoid in severe renal or hepatic impairment
• Temporarily discontinue before contrast imaging procedures if advised
• Use cautiously in elderly patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Use only if clearly needed (often continued under supervision in gestational diabetes)
• Lactation: Generally considered safe
• Pediatrics: Use under specialist guidance
• Elderly: Requires regular renal monitoring

Storage

• Store below 25°C
• Protect from moisture and light
• Keep in original packaging
• Keep out of reach of children.