Mezest Tablet 40 mg contains Megestrol Acetate, a synthetic progestin used for the management of appetite loss, weight loss, and certain hormone-related conditions. It is commonly prescribed for patients suffering from cancer-associated cachexia, chronic illness-related wasting, and selected gynecological disorders. Mezest helps stimulate appetite, promote weight gain, and improve overall nutritional status.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Megestrol Acetate 40 mg

Mechanism of Action

Megestrol Acetate acts as a progestational agent with multiple physiological effects:

• Stimulates appetite by acting on the hypothalamic feeding center
• Modifies metabolism to support weight gain
• Exerts anti-estrogenic activity in certain tissues
• Improves energy intake and reduces weight loss in chronic disease states

These actions contribute to improved nutritional and clinical outcomes in debilitated patients.

Indications

Mezest Tablet is indicated for:

• Cancer-related anorexia and cachexia
• Unintentional weight loss in chronic diseases
• HIV/AIDS-associated wasting syndrome
• Supportive care in advanced illness with poor appetite
• Selected hormonal and gynecological conditions as prescribed by a physician

Dosage and Administration

• Dosage is individualized based on patient condition and medical advice.
• Usually taken orally once or multiple times daily depending on indication.
• Can be taken with or without food.
• Consistent use is important for achieving appetite and weight improvement.

Benefits

• Enhances appetite and food intake
• Promotes gradual weight gain
• Improves nutritional status in chronic illness
• Supports quality of life in debilitated patients

Possible Side Effects

Common side effects may include:

• Increased appetite and weight gain
• Fluid retention or swelling
• Nausea
• Mood changes
• Fatigue

Less common but serious effects may include thromboembolic events and hormonal imbalance.

Precautions

• Use with caution in patients with a history of blood clots
• Not recommended during pregnancy unless clearly indicated
• Monitor for signs of fluid retention or heart failure
• Caution in patients with diabetes, liver disease, or cardiovascular conditions
• Long-term use should be under medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Mege strol Acetate may interact with:

• Anticoagulants (e.g., warfarin)
• Antidiabetic drugs
• Hormonal therapies
• Enzyme-inducing medications

Inform your healthcare provider about all ongoing medications.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.