Miragon Tablet 25 mg contains Mirabegron, a selective β3-adrenoceptor agonist used for the management of overactive bladder (OAB) with symptoms of urgency, frequency, and urge incontinence. Mirabegron works by relaxing the detrusor muscle of the bladder during the storage phase, increasing bladder capacity and reducing the frequency of urination, thereby improving quality of life in patients with OAB.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Mirabegron 25 mg

Mechanism of Action

Mirabegron selectively stimulates β3-adrenoceptors in the bladder, which relaxes the detrusor smooth muscle during the storage phase. This increases bladder capacity and helps reduce urinary urgency, frequency, and incontinence episodes. Unlike antimuscarinic drugs, Mirabegron does not block acetylcholine receptors, which reduces the risk of dry mouth, constipation, and other common anticholinergic side effects.

Indications

Miragon Tablet 25 mg is indicated for:

• Management of overactive bladder (OAB)
• Reducing urinary urgency, frequency, and urge incontinence
• Improving overall bladder control and patient comfort

Dosage and Administration

• Recommended starting dose: 25 mg orally once daily
• Can be increased to 50 mg once daily based on efficacy and tolerability
• Swallow tablets whole with water, with or without food
• Dose adjustment may be required in patients with moderate renal or hepatic impairment
• Regular follow-up with a physician is recommended to monitor response

Benefits

• Reduces urinary urgency, frequency, and urge incontinence
• Increases bladder capacity and improves storage function
• Well-tolerated with fewer anticholinergic side effects
• Improves quality of life for patients with OAB
• Convenient once-daily oral dosing

Side Effects

Common side effects may include:

• Increased blood pressure
• Nasopharyngitis (common cold symptoms)
• Headache
• Dizziness

Rare but serious side effects:

• Palpitations
• Severe hypertension
• Urinary retention

Precautions

• Monitor blood pressure regularly, especially in hypertensive patients
• Use with caution in patients with severe renal or hepatic impairment
• Not recommended in severe uncontrolled hypertension
• Inform your doctor of any heart conditions before starting treatment
• Avoid abrupt discontinuation without medical advice

Contraindications

• Hypersensitivity to Mirabegron or any component of the formulation
• Severe uncontrolled hypertension

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• CYP2D6 substrates (Mirabegron may increase their plasma levels)
• Antihypertensive medications (monitor blood pressure)
• Other drugs affecting renal excretion

Storage

• Store below 30°C
• Keep in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.