Nebicard Tablet 2.5 mg contains Nebivolol Hydrochloride, a highly selective beta-1 adrenergic receptor blocker (beta-blocker) used primarily to manage hypertension and other cardiovascular conditions. Nebivolol works not only by reducing heart rate and blood pressure but also by promoting vasodilation, which helps improve blood flow and reduces cardiac workload.

This low-dose formulation of Nebivolol is ideal for initiating therapy or maintaining blood pressure control in patients requiring careful titration. Nebicard 2.5 mg offers effective cardiovascular protection while minimizing side effects commonly associated with higher doses of beta-blockers.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Nebivolol Hydrochloride 2.5 mg

Mechanism of Action

Nebivolol selectively blocks beta-1 adrenergic receptors in the heart, which reduces the effects of adrenaline and noradrenaline. This leads to a decrease in heart rate, myocardial contractility, and cardiac output, effectively lowering blood pressure.

Additionally, Nebivolol stimulates the release of nitric oxide (NO) from the endothelium, promoting vasodilation. This dual mechanism not only reduces systemic vascular resistance but also enhances oxygen delivery to tissues, providing added cardiovascular benefits.

Indications

Nebicard Tablet 2.5 mg is indicated for:

• Essential hypertension (high blood pressure)

• Heart failure as part of combination therapy

• Prevention of angina (chest pain due to heart disease)

• Management of cardiovascular risk in patients with certain heart conditions

It may also be prescribed for other conditions at the physician’s discretion based on individual cardiovascular risk profiles.

Dosage and Administration

The dosage should be determined by a physician based on the patient’s blood pressure, heart rate, and overall cardiovascular status. Nebicard Tablet 2.5 mg is usually taken once daily, preferably at the same time each day, with or without food.

It is important to swallow the tablet whole with water. Patients should not discontinue the medication abruptly, as sudden withdrawal may exacerbate heart problems. Dose adjustments may be required for patients with kidney or liver impairment.

Benefits

• Effectively lowers blood pressure and reduces cardiovascular strain

• Improves endothelial function through nitric oxide-mediated vasodilation

• Reduces risk of heart failure progression and angina

• Well-tolerated at low doses

• Once-daily dosing for convenience and adherence

Possible Side Effects

Common side effects may include:

• Fatigue or drowsiness

• Dizziness

• Headache

• Mild gastrointestinal disturbances

• Slow heart rate (bradycardia)

Serious but rare side effects can include severe hypotension, fainting, or worsening heart failure. Patients should seek immediate medical attention if they experience chest pain, severe dizziness, or shortness of breath.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with heart failure, severe bradycardia, or conduction abnormalities.

• Monitor blood pressure and heart rate regularly.

• Avoid abrupt discontinuation to prevent rebound hypertension or cardiac events.

• Inform the physician about other medications, particularly other beta-blockers or antihypertensive drugs.

• Not recommended during pregnancy or breastfeeding unless prescribed by a physician.

Storage

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Nebicard Tablet 2.5 mg offers safe and effective management of hypertension and cardiovascular conditions, supporting heart health and overall cardiovascular well-being under proper medical supervision.