Nitrovas Ointment 0.40% contains Nitroglycerin, a vasodilator commonly used for the treatment of anal fissures and related pain. It works by relaxing smooth muscles and improving blood flow to the affected area, which promotes healing and reduces discomfort. This topical formulation is specifically designed for localized application, ensuring targeted relief with minimal systemic absorption.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Nitroglycerin 0.40% (ointment)

Mechanism of Action

Nitroglycerin is converted into nitric oxide in the body, which leads to relaxation of smooth muscle cells. In the case of anal fissures, it reduces the pressure in the anal sphincter and increases blood flow to the area. This helps relieve pain, reduce spasms, and accelerate the healing process.

Indications

Nitrovas Ointment 0.40% is indicated for:

• Chronic anal fissures
• Pain associated with anal fissures
• Anal sphincter spasm
• Conditions requiring improved local blood circulation

Dosage and Administration

• Apply as directed by a physician.
• A small amount of ointment should be applied to the affected area, usually twice daily.
• Wash hands before and after application.
• Avoid contact with eyes and mucous membranes.
• Do not exceed the recommended dose to prevent side effects.

Benefits

• Provides effective relief from anal pain and discomfort
• Promotes healing of fissures
• Reduces anal sphincter pressure and spasms
• Improves blood circulation to the affected area
• Easy-to-use topical formulation

Side Effects

Common side effects may include:

• Headache (most common)
• Dizziness
• Burning or irritation at the application site
• Lightheadedness

Serious but rare side effects:

• Severe hypotension (low blood pressure)
• Fainting
• Allergic reactions

Patients should seek medical attention if severe side effects occur.

Precautions and Warnings

• Use cautiously in patients with low blood pressure or cardiovascular conditions.
• Avoid sudden standing up to reduce the risk of dizziness or fainting.
• Do not use in combination with phosphodiesterase inhibitors (e.g., sildenafil) due to risk of severe hypotension.
• Pregnant and breastfeeding women should consult a doctor before use.
• Use only for external application as prescribed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Nitrovas Ointment may interact with:

• Phosphodiesterase inhibitors (e.g., sildenafil, tadalafil)
• Antihypertensive drugs
• Other nitrate-containing medications
• Alcohol (may increase hypotensive effects)

Always inform your healthcare provider about any medications you are taking.

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.