Novatron Tablet 8 mg contains Ondansetron, a selective 5-HT3 (serotonin) receptor antagonist used to prevent and treat nausea and vomiting. It is commonly prescribed for nausea and vomiting associated with chemotherapy, radiotherapy, surgery, and certain gastrointestinal conditions.

Ondansetron works by blocking serotonin receptors in both the gastrointestinal tract and the central nervous system. Since serotonin plays a key role in triggering the vomiting reflex, blocking its action helps control nausea effectively.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Prevents chemotherapy-induced nausea and vomiting

• Reduces post-operative nausea and vomiting

• Effective for radiation-induced nausea

• Fast onset of action

• Generally well tolerated

Indications

Novatron Tablet 8 mg is indicated for:

• Prevention of nausea and vomiting associated with chemotherapy

• Prevention of nausea and vomiting associated with radiotherapy

• Prevention and treatment of post-operative nausea and vomiting

• Management of severe nausea as prescribed by a healthcare professional,

Dosage and Administration

• The usual adult dose for chemotherapy-induced nausea is 8 mg taken 30 minutes before treatment, followed by additional doses as prescribed.

• For post-operative nausea, 8 mg may be given before surgery or as directed by a physician.

• Swallow the tablet whole with water.

• Dosage may vary depending on age, medical condition, and treatment type.

Always follow the healthcare provider’s instructions regarding dose and duration.

Mechanism of Action

Ondansetron selectively blocks 5-HT3 receptors located peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the brain. By preventing serotonin from binding to these receptors, it interrupts the vomiting reflex pathway, thereby reducing nausea and vomiting.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Safety Information

Contraindications:

• Hypersensitivity to ondansetron or other 5-HT3 antagonists

• Concomitant use with apomorphine

Warnings and precautions:

• May cause QT interval prolongation; use cautiously in patients with cardiac disorders

• Monitor in patients with electrolyte imbalances

• Use cautiously in patients with liver impairment

Common side effects may include:

• Headache

• Constipation

• Dizziness

• Fatigue

Serious side effects are rare but may include allergic reactions or cardiac rhythm disturbances.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.