Pizo-A Tablet 1.5 mg contains Pizotifen, a serotonin receptor antagonist widely used for the preventive treatment of migraine and other recurrent vascular headaches. This higher-strength formulation is designed for patients who require a stronger maintenance dose for effective migraine prophylaxis. Regular use of Pizo-A Tablet helps reduce the frequency, intensity, and duration of migraine attacks, thereby improving overall quality of life.

Migraine is a chronic neurological disorder characterized by recurring episodes of moderate to severe throbbing headache, often associated with nausea, vomiting, and sensitivity to light or sound. Pizo-A Tablet 1.5 mg is not intended to relieve an ongoing migraine attack but is prescribed as a long-term preventive therapy to minimize future episodes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pizotifen 1.5 mg per tablet

Mechanism of Action

Pizotifen primarily works by blocking serotonin (5-HT2) receptors. Serotonin plays an important role in the development of migraine through its effect on blood vessels in the brain. By inhibiting serotonin activity, Pizo-A helps prevent the vascular changes that trigger migraine attacks. Additionally, it possesses mild antihistaminic and anticholinergic properties, contributing to its therapeutic benefits in migraine prevention.

Indications

Pizo-A Tablet 1.5 mg is indicated for:

• Prophylactic treatment of migraine

• Prevention of recurrent vascular headaches

• Long-term management of chronic migraine under physician supervision

Dosage and Administration

The dosage of Pizo-A Tablet 1.5 mg should be individualized according to the patient’s clinical condition and response to therapy.

• Usually taken once daily, often at night to reduce daytime drowsiness.

• Tablets should be swallowed whole with water.

• It may be taken with food to minimize gastric discomfort.

• Treatment is generally long-term for effective prevention.

• Do not discontinue abruptly without medical advice, as gradual dose reduction may be necessary.

Always follow your healthcare provider’s instructions regarding dose and duration.

Precautions and Warnings

• Use cautiously in patients with glaucoma or urinary retention.

• Caution is advised in patients with liver impairment.

• May cause drowsiness; avoid driving or operating heavy machinery if affected.

• Alcohol should be avoided as it may increase sedation.

• Increased appetite and weight gain may occur during prolonged use.

Women who are pregnant or breastfeeding should consult a doctor before using this medication.

Possible Side Effects

Like all medicines, Pizo-A Tablet may cause side effects in some individuals. Commonly reported effects include:

• Increased appetite

• Weight gain

• Drowsiness or fatigue

• Dry mouth

• Constipation

Most side effects are mild and often diminish with continued use. Seek medical attention if severe or unusual reactions occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 30°C in a dry place.

• Protect from light and moisture.

• Keep out of reach of children.

Conclusion

Pizo-A Tablet 1.5 mg (Pizotifen) is an effective preventive therapy for migraine sufferers who require a higher maintenance dose. With regular use under medical supervision, it helps reduce migraine frequency and severity, promoting better daily functioning and overall well-being.