Pulfibro Tablet 267 mg contains Pirfenidone, an antifibrotic and anti-inflammatory agent used for the management of idiopathic pulmonary fibrosis (IPF), a chronic lung disease characterized by progressive scarring of lung tissue. By slowing the progression of fibrosis, Pirfenidone helps preserve lung function, improve quality of life, and reduce the decline in respiratory capacity in patients with IPF.

Pulfibro is prescribed as part of a long-term treatment plan and works at the molecular level to inhibit key pathways involved in fibrotic tissue formation and inflammation. Regular use of Pulfibro Tablet can help stabilize lung function, reduce disease-related symptoms such as breathlessness and fatigue, and minimize the rate of disease progression.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Pirfenidone – 267 mg

Mechanism of Action

Pirfenidone exhibits antifibrotic and anti-inflammatory properties by modulating multiple molecular pathways associated with lung fibrosis:

• Inhibits fibroblast proliferation and collagen synthesis, preventing excessive scarring in lung tissue

• Reduces the production of pro-fibrotic cytokines, including transforming growth factor-beta (TGF-β)

• Controls inflammatory processes that contribute to lung tissue damage

Through these actions, Pulfibro slows the progression of IPF, helping patients maintain better lung function over time.

Indications

Pulfibro Tablet 267 mg is indicated for:

• Idiopathic pulmonary fibrosis (IPF) in adults

• Slowing disease progression and preserving lung function in patients with mild to moderate IPF

• Management of symptoms associated with pulmonary fibrosis, including breathlessness, fatigue, and reduced exercise tolerance

It is not a cure for IPF but helps reduce the rate of lung function decline and improve quality of life.

Dosage and Administration

Pulfibro Tablet should be taken according to a physician’s instructions:

• The usual starting dose is gradually titrated to minimize side effects

• Tablets should be taken orally with food to improve absorption and reduce gastrointestinal discomfort

• Follow the prescribed dosage schedule strictly for effective management of IPF

• Do not alter the dose without consulting a healthcare provider

Benefits

• Slows the progression of idiopathic pulmonary fibrosis

• Reduces lung tissue scarring and fibrosis

• Improves respiratory function and exercise tolerance

• Supports better quality of life for patients with chronic lung disease

• Well-studied safety and efficacy profile in IPF management

Possible Side Effects

Common side effects may include:

• Nausea, vomiting, or loss of appetite

• Fatigue and dizziness

• Rash or skin sensitivity to sunlight

• Liver enzyme abnormalities

Patients should report severe or persistent side effects to their doctor promptly. Regular liver function tests may be recommended during treatment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use with caution in patients with liver or kidney impairment

• Avoid excessive sun exposure due to photosensitivity

• Not recommended for acute respiratory infections

• Inform your physician of all medications being taken to prevent potential interactions

• Pregnant or breastfeeding women should consult a doctor before use

Storage

Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.