Sitacret-M Tablet 50 mg + 500 mg is a combination oral antidiabetic medication containing Sitagliptin 50 mg and Metformin Hydrochloride 500 mg, designed for the management of type 2 diabetes mellitus.

• Sitagliptin is a DPP-4 inhibitor that enhances the body’s natural incretin hormones, stimulating insulin release after meals and reducing glucagon production to lower blood sugar.

• Metformin Hydrochloride is a biguanide that reduces hepatic glucose production and improves insulin sensitivity, helping to control both fasting and postprandial blood glucose.

Together, these agents provide complementary mechanisms of action, offering enhanced glycemic control in patients whose blood sugar is not adequately managed by diet, exercise, or monotherapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features and Benefits

• Active Ingredients: Sitagliptin 50 mg + Metformin Hydrochloride 500 mg

• Primary Use: Management of type 2 diabetes mellitus

• Mechanism of Action:

  • Sitagliptin increases incretin hormones → stimulates insulin release and suppresses glucagon

  • Metformin reduces liver glucose production and improves insulin sensitivity

• Formulation: Oral tablet for convenient, once or twice daily dosing

• Dual Action: Provides fast and sustained blood sugar control

Benefits

• Controls both fasting and post-meal blood sugar levels

• Reduces risk of hyperglycemia and diabetes-related complications

• Combines two effective antidiabetic mechanisms in a single tablet for patient convenience

• Supports long-term glycemic management and metabolic health

• Well tolerated with low risk of hypoglycemia when used alone or with lifestyle measures

Recommended Dosage

• Adults: Typically 1 tablet once or twice daily, with meals, or as prescribed by a healthcare professional

• Tablets should be taken with food to reduce gastrointestinal side effects

• Dose adjustments may be needed based on renal function, blood glucose levels, and treatment response

Important: Regular monitoring of blood sugar is recommended to achieve optimal glycemic control. Do not skip meals after taking this medication.

Safety Information

Sitacret-M Tablet is generally well tolerated but may cause:

• Common effects: Nausea, diarrhea, headache, mild gastrointestinal discomfort

• Less common effects: Hypoglycemia (mainly if combined with other antidiabetic drugs), dizziness, joint pain

• Precautions: Use with caution in patients with renal impairment, liver disease, or a history of lactic acidosis. Inform your doctor of any pancreatitis or allergic history

Patients should maintain a healthy diet and regular exercise to enhance the medication’s effectiveness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store Sitacret-M Tablet 50 mg + 500 mg in a cool, dry place, away from sunlight and moisture. Keep out of reach of children. Proper storage ensures tablet stability and effectiveness.

Conclusion

Sitacret-M Tablet 50 mg + 500 mg by SK Pharma is an effective combination therapy for type 2 diabetes. By merging Sitagliptin’s incretin-enhancing effect with Metformin’s insulin-sensitizing action, it provides comprehensive blood sugar control, improves metabolic health, and helps reduce the risk of diabetes-related complications.