Symbion Inhalation Capsule 400 mcg+12 mcg is a high-strength combination therapy containing Budesonide and Formoterol Fumarate, formulated for the maintenance treatment of moderate to severe asthma and chronic obstructive pulmonary disease (COPD). This advanced dual-action therapy provides powerful anti-inflammatory control along with prolonged bronchodilation to help maintain optimal respiratory function.

Chronic airway diseases such as asthma and COPD are associated with persistent inflammation and narrowing of the airways, leading to breathlessness, wheezing, coughing, and chest tightness. Symbion Inhalation Capsule is designed to address both key components of these conditions—airway inflammation and bronchospasm—ensuring comprehensive disease management and improved quality of life.

This inhalation capsule is intended for use with a compatible dry powder inhaler device to deliver the medication directly to the lungs for targeted and effective action.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Symbion Inhalation Capsule 400 mcg+12 mcg is indicated for:

• Maintenance treatment of moderate to severe bronchial asthma

• Patients inadequately controlled on inhaled corticosteroids alone

• Maintenance treatment of chronic obstructive pulmonary disease (COPD)

• Reduction in frequency and severity of COPD exacerbations

This medication is not intended for the immediate relief of acute bronchospasm or sudden asthma attacks.

Therapeutic Class

Combined inhaled corticosteroid (ICS) and long-acting beta2-agonist (LABA)

Pharmacology

Budesonide is a potent inhaled corticosteroid that works by suppressing airway inflammation. It inhibits the release of inflammatory mediators, reduces mucosal edema, and decreases mucus secretion. Regular use helps maintain long-term control of inflammatory airway diseases and reduces exacerbations.

Formoterol Fumarate is a selective long-acting beta2-adrenergic agonist. It relaxes bronchial smooth muscle by stimulating beta2 receptors in the lungs, resulting in sustained bronchodilation. Formoterol has a rapid onset of action and provides relief for up to 12 hours.

The synergistic combination of Budesonide and Formoterol ensures both inflammation control and sustained airway relaxation, leading to improved lung function and symptom control.

Dosage and Administration

The dosage should be determined by a registered physician based on disease severity and individual patient response. Typically, one inhalation capsule is used once or twice daily as prescribed.

Important instructions:

• The capsule must be used only with a suitable dry powder inhaler device.

• The capsule should not be swallowed.

• Rinse the mouth with water after inhalation to reduce the risk of oral candidiasis.

Regular adherence to prescribed therapy is essential for optimal results.

Precautions

• Not suitable for the relief of acute asthma symptoms.

• Use cautiously in patients with cardiovascular disorders, diabetes, hyperthyroidism, or seizure disorders.

• Avoid abrupt discontinuation without medical supervision.

Side Effects

Common side effects may include:

• Oral candidiasis

• Hoarseness

• Throat irritation

• Headache

• Tremor

• Palpitations

Most side effects are mild and can be minimized with correct inhalation technique and proper mouth rinsing after use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Pregnancy and Lactation

Use during pregnancy and breastfeeding should only be considered if clearly necessary and under medical supervision.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Symbion Inhalation Capsule 400 mcg+12 mcg provides strong and effective long-term control of asthma and COPD, helping patients breathe easier and maintain better respiratory stability.