Tranexil Injection 500 mg/5 ml is an antifibrinolytic medication containing Tranexamic Acid, used to prevent and control excessive bleeding associated with various medical and surgical conditions. It works by stabilizing blood clots and reducing abnormal or excessive blood loss, making it a valuable option in both emergency and elective clinical settings.

This injectable formulation is especially useful when rapid action is required or when oral administration is not feasible.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Tranexamic Acid 500 mg per 5 ml ampoule

Indications

Tranexil Injection is indicated for the prevention and treatment of bleeding in conditions such as:

• Heavy menstrual bleeding (menorrhagia)

• Surgical bleeding, including orthopedic, cardiac, dental, and gynecological surgeries

• Trauma-related hemorrhage

• Postpartum hemorrhage

• Bleeding associated with fibrinolytic disorders

• Epistaxis and other mucosal bleeding conditions

Therapeutic Class

• Antifibrinolytic agent

Pharmacology

Tranexamic Acid is a synthetic derivative of the amino acid lysine. It exerts its effect by reversibly blocking lysine-binding sites on plasminogen molecules. This action prevents the conversion of plasminogen to plasmin, the enzyme responsible for breaking down fibrin clots. As a result, fibrin clots are stabilized, and excessive bleeding is reduced.

Tranexamic Acid does not initiate clot formation but helps preserve existing clots at sites of vascular injury. This targeted mechanism makes it effective in controlling bleeding without significantly increasing the risk of unwanted thrombosis when used appropriately.

Dosage and Administration

• The dose and duration depend on the indication, severity of bleeding, and patient condition

• Administered by slow intravenous injection or infusion

• Should be given under the supervision of a qualified healthcare professional

Benefits

• Rapid and effective control of bleeding

• Useful in a wide range of surgical and medical bleeding conditions

• Helps reduce the need for blood transfusions

• Suitable for patients unable to take oral medication

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Dose adjustment may be required in patients with renal impairment

• Use during pregnancy only if clearly indicated

• Can be used during breastfeeding under medical advice

Possible Side Effects

Common side effects may include:

• Nausea

• Vomiting

• Diarrhea

• Dizziness

Rare but serious adverse effects may include visual disturbances, hypersensitivity reactions, or thromboembolic events, particularly in patients with predisposing risk factors.

Storage

• Store below 30°C

• Protect from light

• Do not freeze

• Keep out of reach of children

Precautions

• Use with caution in patients with a history of thromboembolic disease

• Renal function should be monitored during prolonged use

• Rapid intravenous injection should be avoided to reduce the risk of hypotension.