Zervin 0.24% Eye Drop is an ophthalmic antihistamine formulated for the relief of ocular itching associated with allergic conjunctivitis. It contains Cetirizine Hydrochloride 0.24%, a potent H1 histamine receptor antagonist that selectively inhibits histamine-mediated allergic responses in the eye. This helps reduce redness, itching, and discomfort caused by seasonal or perennial ocular allergies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Ophthalmic Anti-Allergic Preparation

• H1 Receptor Antagonist

Pharmacology

Cetirizine Hydrochloride, the active component in Zervin, works by blocking H1 histamine receptors on ocular tissues. This antagonism prevents the typical allergic symptoms of redness, itching, and tearing. In vivo and ex vivo studies in animals show that cetirizine has minimal anticholinergic or antiserotonergic activity, making it highly selective and well tolerated. In vitro studies confirm negligible binding to receptors other than H1, highlighting its targeted action for ocular allergy relief.

Indications

Zervin 0.24% Eye Drop is indicated for:

• Ocular itching associated with allergic conjunctivitis in adults and children aged 2 years and above

Dosage & Administration

• Instill one drop in each affected eye twice daily, approximately 8 hours apart

• Shake well before use

• Avoid contact with the dropper tip to prevent contamination

• Do not use while wearing contact lenses; remove lenses before administration and wait at least 10 minutes before reinserting

Contraindications

• No specific contraindications reported

Pregnancy & Lactation

• Pregnancy: Use only if the potential benefits outweigh potential risks to the fetus

• Lactation: Safety during breastfeeding is not established; consult a physician before use

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Prevent contamination of the dropper tip

• Avoid instillation while wearing contact lenses; benzalkonium chloride, the preservative, may be absorbed by soft lenses

• Use caution in patients with ocular infections or conditions that may be aggravated by topical antihistamines

Side Effects

Zervin 0.24% Eye Drop is generally well tolerated. Mild, transient side effects may occur, including:

• Eye irritation or burning sensation

• Mild stinging on instillation

• Temporary blurred vision

Use in Special Populations

• Pediatric Use: Safe and effective for children aged 2 years and older

• Geriatric Use: No significant differences in safety or efficacy compared to younger adults

Storage

• Store at 15°C to 25°C, protected from light and moisture

• Keep out of reach of children

• Keep the bottle tightly closed when not in use.