Aristofol Fe Tablet 308 mg + 350 mcg is a combination of Ferrous Fumarate (308 mg) and Folic Acid (350 mcg) formulated to prevent and treat iron and folic acid deficiencies. This combination is particularly effective in managing iron-deficiency anemia and megaloblastic anemia caused by folic acid deficiency. Iron is an essential component of hemoglobin, which is necessary for oxygen transport in the blood, while folic acid plays a critical role in DNA synthesis, red blood cell formation, and overall hematopoiesis.

Aristofol Fe helps restore hemoglobin levels, improves energy, reduces fatigue, and supports normal growth and development in children, adolescents, and pregnant women. The tablet is convenient for daily use and ensures adequate supplementation of both iron and folic acid.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Aristofol Fe Tablet is indicated for:

• Prevention and treatment of iron deficiency anemia

• Megaloblastic anemia due to folic acid deficiency

• Anemia during pregnancy, lactation, or periods of increased iron requirement

• Supportive therapy in children, adolescents, and adults with inadequate dietary intake of iron and folic acid

• Recovery from blood loss due to surgery or trauma

Therapeutic Class

Iron and Vitamin Supplement

Pharmacology

Ferrous Fumarate:
Ferrous fumarate is an oral iron preparation that provides elemental iron necessary for hemoglobin and red blood cell production. Iron is absorbed primarily in the duodenum and proximal jejunum and is incorporated into hemoglobin and myoglobin, restoring oxygen transport capacity.

Folic Acid:
Folic acid (vitamin B9) is essential for nucleic acid synthesis and red blood cell maturation. It helps prevent megaloblastic anemia and supports DNA synthesis during periods of rapid cell division, such as pregnancy and growth in children.

The combination of iron and folic acid addresses both components of anemia, ensuring effective and rapid correction of hemoglobin levels and replenishment of iron stores.

Dosage and Administration

Adults:

• 1 tablet daily or as directed by a healthcare professional

• Take preferably after meals to reduce gastrointestinal discomfort

• Swallow whole with water

Pregnancy and Lactation:

• Recommended as a daily supplement to meet increased iron and folic acid needs

• Dosage may be adjusted by a physician based on hemoglobin levels and clinical status

Children:

• Use only under medical supervision; dosage depends on age and iron requirements

Drug Interactions

• Antacids, calcium supplements, and some antibiotics (tetracyclines, fluoroquinolones) may reduce iron absorption

• Vitamin C enhances iron absorption and may be taken concurrently

• Concurrent use with methotrexate or anticonvulsants may require monitoring of folic acid levels

Contraindications

• Known hypersensitivity to ferrous fumarate, folic acid, or any excipients in the tablet

• Hemochromatosis or other iron overload disorders

• Megaloblastic anemia due to vitamin B12 deficiency (without B12 correction)

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common:

• Nausea, vomiting, or stomach upset

• Constipation or dark-colored stools

• Mild diarrhea or abdominal discomfort

Rare:

• Allergic reactions (rash, itching)

• Severe gastrointestinal irritation with high doses

Precautions and Warnings

• Avoid excessive iron intake to prevent toxicity

• Monitor hemoglobin and hematocrit levels during prolonged therapy

• Keep out of reach of children, as iron overdose can be fatal

Pregnancy and Lactation

• Considered safe and recommended during pregnancy to prevent maternal anemia and support fetal growth

• Supports lactating mothers in maintaining adequate iron and folate levels

Storage Conditions

Store in a cool, dry place away from direct sunlight and moisture.
Keep out of reach of children.

Mode of Action

• Ferrous Fumarate: Replenishes iron stores, promotes hemoglobin synthesis, and restores oxygen-carrying capacity of blood

• Folic Acid: Supports red blood cell maturation and DNA synthesis, preventing megaloblastic anemia

The combination ensures rapid correction of iron and folate deficiencies, improving energy, vitality, and overall hematologic health.