Azmasol Bexicap 200 mcg is a short-acting selective β2-adrenoceptor stimulant used as a fast-acting bronchodilator for the management of reversible airway obstruction. It is effective in relieving bronchospasm associated with asthma, chronic bronchitis, emphysema, and other obstructive airway diseases. Due to its rapid onset of action, Azmasol Bexicap 200 mcg is suitable for both acute symptom relief and preventive use, including exercise-induced bronchospasm.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Azmasol Bexicap 200 mcg is indicated for use as a bronchodilator in:

• Bronchial asthma

• Chronic bronchitis

• Emphysema

• Other conditions associated with reversible airway obstruction

• Exercise-induced asthma

Therapeutic Class

Short-acting selective β2-adrenoceptor stimulants

Pharmacology

Azmasol Bexicap 200 mcg contains a selective beta-2 adrenergic agonist. At therapeutic doses, it predominantly stimulates β2-adrenoceptors in bronchial smooth muscle, producing effective bronchodilation with minimal action on β1-adrenoceptors of the heart. The onset of bronchodilation occurs within 5 minutes and lasts for approximately 4–6 hours.
Additionally, it exhibits anti-inflammatory properties by inhibiting mast cell mediator release, including histamine, neutrophil chemotactic factor, and prostaglandin D2, which contribute to bronchoconstriction.

Dosage and Administration

Oral (Tablet/Syrup):

• Children 2–6 years: 2.5 ml syrup, 3–4 times daily

• Children 6–12 years: 5 ml syrup, 3–4 times daily

• Over 12 years: 5–10 ml syrup or 2–4 mg tablet, 3–4 times daily

• Adults: 2–4 mg tablet, 3–4 times daily

• Maximum single dose: 8 mg

Inhalation Capsule (Bexicap):

• Adults: 1–2 capsules (200 mcg each) every 4–6 hours as required

• Children (≥4 years): 1 capsule 3–4 times daily; may increase to 2 capsules if necessary

• Exercise-induced asthma:

  • Adults: 400 mcg

  • Children: 200 mcg, 15–30 minutes before exercise

Nebulizer Solution:

• Adults & elderly: 2.5–5 mg up to 4 times daily

• Children under 12 years: 2.5 mg up to 4 times daily

Injection:
Administered via subcutaneous, intramuscular, slow intravenous injection, or continuous IV infusion under medical supervision. Dosage varies by route and clinical condition.

Contraindications

Azmasol Bexicap 200 mcg is contraindicated in patients with known hypersensitivity to the drug or any of its components.

Side Effects

Possible side effects include:

• Fine skeletal muscle tremor

• Palpitations

• Muscle cramps

• Tachycardia

• Headache

• Nervousness and peripheral vasodilatation, especially at higher doses

Pregnancy and Lactation

• Pregnancy: Use only if the potential benefit outweighs the potential risk to the fetus.

• Lactation: It is not known whether the drug is excreted in human milk. A decision should be made to discontinue either breastfeeding or the drug, considering maternal benefit.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

Use with caution in patients with:

• Cardiovascular disease

• Hypertension

• Hyperthyroidism

• Diabetes mellitus

• Occlusive vascular disorders

• Hypokalaemia
  Prolonged high-dose use may lead to tachyphylaxis and reduced therapeutic response.

Overdose

Symptoms of overdose include headache, nausea, vomiting, tremor, angina, and tachycardia. A cardio-selective beta-blocker may be used as an antidote with caution, especially in patients prone to bronchospasm.

Storage Conditions

Store below 30°C. Protect from light and moisture. Keep out of the reach of children.

Mode of Action

Azmasol Bexicap 200 mcg stimulates β2-adrenergic receptors in bronchial smooth muscle, leading to relaxation of airway muscles and improved airflow. This results in rapid relief from bronchospasm and improved pulmonary function.