Diretic Tablet 20 mg+50 mg is a combination diuretic medication containing Furosemide 20 mg and Spironolactone 50 mg, designed for the management of fluid retention (edema) associated with heart, liver, or kidney disorders. This synergistic formulation combines a loop diuretic (Furosemide) and a potassium-sparing diuretic (Spironolactone), providing potent removal of excess fluid while minimizing the risk of potassium imbalance.

Furosemide acts on the loop of Henle in the kidneys, increasing the excretion of sodium, chloride, and water, which helps reduce swelling, blood pressure, and fluid accumulation. Spironolactone works in the distal renal tubules to block aldosterone, preventing potassium loss while promoting sodium and water excretion. Together, these two agents offer effective fluid management with a balanced approach to electrolytes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Diretic Tablet 20 mg+50 mg is indicated for:

• Treatment of edema associated with congestive heart failure, liver cirrhosis, or nephrotic syndrome

• Management of hypertension, particularly in patients who require diuretic therapy

• Prevention of potassium depletion when high-dose loop diuretics are used

• Management of ascites related to liver disease

It is particularly beneficial for patients requiring potent diuresis without significant potassium loss.

Dosage and Administration

• Adults: Typically, one tablet daily or as prescribed by a physician, based on the severity of fluid retention and electrolyte status.

• Dose adjustments may be required in patients with renal or hepatic impairment.

• Administration: Swallow the tablet whole with a glass of water, preferably in the morning to prevent nocturnal urination.

• Regular monitoring of electrolytes, kidney function, and blood pressure is essential during therapy.

Patients should maintain adequate fluid intake unless otherwise directed and avoid excessive salt intake, which may reduce the effectiveness of the medication.

Precautions

• Contraindicated in patients with anuria, severe kidney impairment, hyperkalemia, or hypersensitivity to Furosemide, Spironolactone, or any tablet component.

• Use cautiously in patients with liver disease, kidney disease, or heart rhythm disorders.

• Monitoring of potassium, sodium, and kidney function is necessary to prevent electrolyte imbalances.

• May interact with medications such as ACE inhibitors, ARBs, or other potassium-sparing drugs—consult a physician before use.

• Pregnant or breastfeeding women should use only under medical supervision.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Diretic Tablet is generally well tolerated, but some patients may experience:

• Electrolyte disturbances (hyperkalemia or hyponatremia)

• Dizziness, headache, or hypotension

• Gastrointestinal upset, nausea, or vomiting

• Increased urination

• Rarely, allergic reactions, rash, or gynecomastia (associated with Spironolactone)

Seek immediate medical attention if severe dehydration, irregular heartbeat, or persistent electrolyte disturbances occur.

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Diretic Tablet 20 mg+50 mg provides effective fluid management and blood pressure control, combining the rapid diuretic action of Furosemide with the potassium-sparing benefits of Spironolactone, making it suitable for patients with edema or hypertension under careful medical supervision.