Elacentra Tablet contains Elacestrant 345 mg, an oral selective estrogen receptor degrader (SERD) used in the treatment of certain types of hormone receptor-positive, HER2-negative breast cancer. It is primarily indicated in postmenopausal women and adult patients with advanced or metastatic disease, especially in cases where prior endocrine therapy has shown resistance or disease progression.

Elacestrant works by targeting estrogen receptors in cancer cells, helping to slow or stop tumor growth. It offers an oral treatment option in advanced breast cancer management under strict oncologist supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Uses

Elacentra Tablet is indicated for:

• ER-positive (estrogen receptor-positive) advanced or metastatic breast cancer
• HER2-negative breast cancer
• Patients with disease progression after prior endocrine therapy
• Treatment of endocrine-resistant breast cancer (as advised by an oncologist)
• Maintenance therapy in selected advanced breast cancer cases

Its use is guided by biomarker status and specialist evaluation.

Mechanism of Action

Elacestrant is a selective estrogen receptor degrader (SERD) that works by:

• Binding to estrogen receptors on cancer cells
• Blocking estrogen signaling that promotes tumor growth
• Promoting degradation of estrogen receptors
• Reducing cancer cell proliferation and survival
• Helping overcome resistance to prior hormonal therapies

This targeted mechanism makes it an important option in hormone-driven breast cancers.

Dosage & Administration

• Recommended dose is as prescribed by an oncologist (commonly once daily oral administration)
• Should be taken at the same time each day for consistent effect
• May be taken with or without food
• Swallow whole with water; do not crush or chew
• Treatment duration depends on patient response and clinical evaluation
• Regular follow-up and monitoring are essential

Side Effects

Common and possible side effects include:

• Nausea and vomiting
• Fatigue or weakness
• Decreased appetite
• Musculoskeletal pain
• Hot flashes
• Diarrhea or constipation
• Elevated liver enzymes
• Increased cholesterol levels

Patients should be monitored regularly during therapy for safety and effectiveness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use only under supervision of an oncology specialist
• Not recommended during pregnancy or breastfeeding
• Liver function monitoring may be required
• Caution in patients with hepatic impairment
• May interact with other medications; inform physician of all ongoing drugs
• Use effective contraception during and after treatment as advised

Storage

• Store below 25°C in a cool and dry place
• Protect from moisture and direct sunlight
• Keep in original packaging
• Do not freeze
• Keep out of reach of children.