Enoparin Injection 4000 Anti-Xa IU/0.4 ml contains Enoxaparin Sodium, a low molecular weight heparin (LMWH) used as an anticoagulant to prevent and treat blood clot formation. It helps reduce the risk of deep vein thrombosis (DVT), pulmonary embolism (PE), and other thromboembolic complications by inhibiting key clotting factors in the blood. This lower-strength formulation is commonly used for prophylactic (preventive) therapy in at-risk patients under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each prefilled syringe (0.4 ml) contains:

• Enoxaparin Sodium 4000 Anti-Xa IU

This provides a predictable and controlled anticoagulant effect suitable for preventive use.

Indications

Enoparin Injection is indicated for:

• Prevention of deep vein thrombosis (DVT) in surgical patients
• Prevention of DVT in immobilized or hospitalized medical patients
• Prevention of pulmonary embolism (PE)
• Thromboprophylaxis in high-risk conditions
• Adjunct management in acute coronary syndrome (as advised by physician)

It is used only under hospital or clinical supervision.

Pharmacological Action

Enoxaparin acts by enhancing the activity of antithrombin III:

• Primarily inhibits Factor Xa, reducing clot formation
• Minimally inhibits Factor IIa (thrombin)
• Prevents conversion of fibrinogen to fibrin
• Provides consistent anticoagulant response with reduced monitoring compared to unfractionated heparin

This mechanism helps prevent the development and progression of harmful blood clots.

Dosage & Administration

• Administered by subcutaneous injection only unless otherwise directed
• Dose depends on indication, body weight, and renal function
• Commonly given once daily for prophylaxis, as prescribed
• Injection sites should be rotated to reduce local irritation

Must be administered by a healthcare professional or trained caregiver.

Side Effects

Possible side effects include:

• Bleeding (most significant risk)
• Bruising or pain at injection site
• Thrombocytopenia (low platelet count)
• Anemia
• Rare allergic reactions

Seek immediate medical attention if unusual bleeding occurs.

Contraindications

• Active major bleeding
• History of heparin-induced thrombocytopenia (HIT)
• Severe thrombocytopenia
• Hypersensitivity to Enoxaparin or heparin derivatives

Precautions & Warnings

• Use cautiously in renal impairment
• Monitor platelet counts during prolonged therapy
• Increased bleeding risk with anticoagulants, antiplatelets, or NSAIDs
• Do not administer intramuscularly
• Dose adjustment may be required in elderly or low-weight patients

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Pregnancy & Lactation

Enoxaparin may be used during pregnancy when clinically required, as it does not cross the placenta. Use only under strict medical supervision.

Storage

• Store below 25°C
• Do not freeze
• Keep in original packaging
• Keep out of reach of children.