Glitin M Tablet 2.5 mg + 850 mg is a combination oral antidiabetic medication containing Linagliptin and Metformin Hydrochloride. It is specifically formulated for adults with type 2 diabetes mellitus to achieve better glycemic control. Linagliptin enhances glucose-dependent insulin secretion and suppresses glucagon levels, while Metformin improves insulin sensitivity and reduces hepatic glucose production. Together, this dual-action therapy helps control both fasting and postprandial blood glucose levels effectively.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Linagliptin 2.5 mg
• Metformin Hydrochloride 850 mg
• Dosage Form: Tablet

Indications

Glitin M Tablet is indicated for:

• Type 2 diabetes mellitus in adults
• Patients inadequately controlled with diet, exercise, and single antidiabetic agents
• Combination therapy to achieve improved glycemic control

Mechanism of Action

• Linagliptin: Inhibits the DPP-4 enzyme, increasing levels of incretin hormones (GLP-1 and GIP), which stimulate insulin secretion and suppress glucagon release after meals.
• Metformin: Reduces hepatic glucose production, increases peripheral glucose uptake, and improves insulin sensitivity.

This complementary mechanism helps maintain stable blood sugar levels throughout the day and reduces fluctuations.

Dosage and Administration

• Take as prescribed by a healthcare professional.
• Typically administered once or twice daily with meals to minimize gastrointestinal discomfort.
• Swallow the tablet whole with water; do not crush or chew.
• Regular blood glucose monitoring is recommended.
• Follow a consistent diet and exercise plan for optimal results.

Benefits

• Provides effective control of fasting and postprandial blood glucose
• Glucose-dependent action of Linagliptin lowers hypoglycemia risk
• Improves insulin sensitivity and reduces liver glucose output
• Combination therapy reduces pill burden for convenience
• Supports weight-neutral or weight-managing effects

Possible Side Effects

Common side effects may include:

• Gastrointestinal disturbances (nausea, diarrhea, abdominal discomfort)
• Headache
• Nasopharyngitis
• Mild hypoglycemia (particularly when combined with other antidiabetic agents)

Seek medical attention immediately if severe side effects occur, such as lactic acidosis or pancreatitis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with kidney or liver impairment.
• Not suitable for type 1 diabetes or diabetic ketoacidosis.
• Regular monitoring of kidney function is advised due to Metformin.
• Inform your doctor about all medications and underlying health conditions.
• Use during pregnancy or breastfeeding only under medical supervision.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.