Hepavax-B Injection 20 mcg/ml is a recombinant DNA (rDNA) Hepatitis B vaccine used for active immunization against Hepatitis B virus (HBV) infection. It stimulates the immune system to produce protective antibodies, helping prevent serious liver diseases such as acute hepatitis, chronic hepatitis, cirrhosis, and hepatocellular carcinoma.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 1 ml contains:

• Hepatitis B surface antigen (rDNA) 20 mcg

This purified vaccine is produced using recombinant DNA technology to ensure safety and effective immune response.

Indications

Hepavax-B Injection is indicated for:

• Prevention of Hepatitis B virus infection
• Routine immunization in adolescents and adults
• Vaccination of healthcare workers and high-risk individuals
• Pre-exposure prophylaxis in non-immune persons
• Post-exposure prophylaxis as part of HBV prevention protocol

Pharmacological Action

The vaccine works by:

• Stimulating the immune system to produce anti-HBs antibodies
• Inducing active immunity against Hepatitis B virus
• Establishing long-term immunological memory
• Preventing viral infection and associated liver complications

Protection is achieved after completion of the full vaccination schedule.

Dosage & Administration

• Administered by intramuscular injection only
• Common schedule: 0, 1, and 6 months (or as per physician recommendation)
• Dose may vary depending on age and clinical guidelines
• Must be administered by a healthcare professional
• Shake well before use
• Do not inject intravenously or intradermally

Side Effects

Possible side effects include:

• Pain, redness, or swelling at injection site
• Mild fever
• Headache
• Fatigue or malaise
• Irritability
• Rare allergic reactions

Contraindications

• Severe allergic reaction to previous dose of Hepatitis B vaccine
• Hypersensitivity to any component of the vaccine
• Acute severe febrile illness (vaccination may be postponed)

Precautions & Warnings

• Complete full vaccination schedule for optimal protection
• Monitor for allergic reactions after administration
• Use cautiously in immunocompromised individuals
• Maintain strict cold chain storage
• Do not mix with other vaccines unless recommended

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Pregnancy & Lactation

Hepatitis B vaccine may be administered during pregnancy and breastfeeding when clearly indicated, especially in high-risk individuals.

Storage

• Store at 2°C to 8°C (do not freeze)
• Protect from light
• Maintain cold chain at all times
• Do not use if frozen or expired
• Keep out of reach of children.