Insul R Injection 40 IU/ml contains recombinant DNA (rDNA) human insulin, a short-acting insulin used for the management of diabetes mellitus. It is primarily indicated for controlling elevated blood glucose levels, especially after meals, and forms an important part of insulin-based therapy in diabetic patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Insulin Human (rDNA) 40 IU/ml

Mechanism of Action

Insulin Human (rDNA) acts by replacing or supplementing the body’s natural insulin. It promotes glucose uptake into muscle and adipose tissues and inhibits hepatic glucose production. This leads to a reduction in blood glucose levels. As a short-acting insulin, it is mainly effective in controlling postprandial (after-meal) blood sugar spikes.

Indications

Insul R Injection is indicated for:

• Type 1 diabetes mellitus
• Type 2 diabetes mellitus when oral antidiabetic medications are inadequate
• Control of post-meal hyperglycemia
• Diabetic ketoacidosis (under hospital supervision)
• Gestational diabetes requiring insulin therapy
• Management of hyperglycemia in hospitalized patients

Dosage and Administration

• Administered via subcutaneous injection
• May be given intravenously in emergency hospital settings under medical supervision
• Usually injected 30 minutes before meals
• Dosage is individualized based on blood glucose monitoring, diet, and clinical condition
• Common injection sites include abdomen, thigh, or upper arm
• Rotate injection sites regularly to prevent lipodystrophy

Possible Side Effects

Common side effects include:

• Hypoglycemia (low blood sugar)
• Weight gain
• Injection site reactions such as redness, swelling, or irritation
• Lipodystrophy at injection sites

Less common but serious effects:

• Severe hypoglycemia leading to confusion, seizures, or loss of consciousness
• Allergic reactions
• Hypokalemia (low potassium levels)

Precautions

• Regular blood glucose monitoring is essential
• Do not skip meals after insulin administration
• Alcohol may increase risk of hypoglycemia
• Dose adjustments may be needed during illness, stress, or dietary changes
• Use cautiously in patients with kidney or liver impairment

Contraindications

• Hypoglycemia episodes
• Known hypersensitivity to human insulin or any component of the formulation

Drug Interactions

• Corticosteroids may increase blood glucose levels
• Beta-blockers may mask symptoms of hypoglycemia
• Oral antidiabetic agents may enhance insulin effect
• Thyroid hormones and diuretics may affect glucose control

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store in a refrigerator at 2°C to 8°C
• Do not freeze
• Protect from heat and direct sunlight
• Once in use, may be kept at room temperature for a limited period as directed

Important Notes

Insul R Injection 40 IU/ml (rDNA Human Insulin) is a short-acting insulin used for effective control of post-meal blood glucose levels. Proper dosing, meal timing, and regular monitoring are essential for safe and effective diabetes management.