LM Tablet 5 mg contains Levamlodipine Maleate, a highly selective calcium channel blocker (CCB) used to treat hypertension and angina pectoris. Levamlodipine is the S-enantiomer of amlodipine, offering enhanced potency with reduced dose requirements, which may help minimize side effects compared to racemic amlodipine.

By inhibiting calcium ion influx into vascular smooth muscle and cardiac muscle, LM Tablet 5 mg promotes arterial vasodilation, leading to a reduction in systemic blood pressure. This mechanism also decreases myocardial oxygen demand, improving symptoms in patients with stable or vasospastic angina.

The once-daily oral tablet provides convenient, long-acting blood pressure control, helping patients maintain target blood pressure and reduce the risk of cardiovascular complications such as stroke, myocardial infarction, and heart failure.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

LM Tablet 5 mg is indicated for:

• Hypertension: As monotherapy or in combination with other antihypertensive agents to lower elevated blood pressure

• Angina pectoris: For chronic stable angina, vasospastic (Prinzmetal’s) angina, and to reduce frequency and severity of anginal attacks

• Cardiovascular risk reduction: As part of long-term management to prevent complications associated with high blood pressure

Therapeutic Class

• Calcium channel blocker (dihydropyridine class)

Pharmacology

Levamlodipine selectively inhibits L-type calcium channels in vascular smooth muscle, resulting in:

• Vasodilation of peripheral arteries, reducing total peripheral resistance

• Lowering of systolic and diastolic blood pressure

• Reduced myocardial oxygen demand, improving angina symptoms

The S-enantiomer is pharmacologically active, providing equivalent or better efficacy than conventional amlodipine but at lower doses, potentially reducing peripheral edema and other dose-related adverse effects.

Dosage & Administration

• Adults (Hypertension): 2.5–5 mg once daily, can be increased to 10 mg based on response

• Adults (Angina): 5 mg once daily, may be titrated to 10 mg as needed

• Can be taken with or without food, preferably at the same time each day for consistent blood levels

• Dose adjustments may be necessary in elderly patients or those with hepatic impairment

Contraindications

• Known hypersensitivity to levamlodipine, amlodipine, or other dihydropyridine derivatives

• Severe hypotension or cardiogenic shock

• Obstruction of the aortic valve or unstable angina requiring intravenous therapy

Side Effects

Common side effects include:

• Headache, dizziness, fatigue

• Peripheral edema, flushing

• Palpitations or mild hypotension

Rare but serious side effects may include: angina exacerbation, arrhythmias, or severe hypotension.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions & Warnings

• Monitor blood pressure regularly

• Use caution in patients with severe aortic stenosis, heart failure, or hepatic impairment

• Concomitant use with other antihypertensives may potentiate blood pressure-lowering effects

Pregnancy & Lactation

• Use only if clearly needed; safety during pregnancy is not well established

• Lactating mothers should avoid use unless benefits outweigh potential risks

Storage

Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.

LM Tablet 5 mg is an effective, convenient, and well-tolerated option for managing hypertension and angina, providing consistent blood pressure control and cardiovascular protection through selective calcium channel blockade.