Milran Tablet 50 mg contains Milnacipran Hydrochloride, a serotonin and norepinephrine reuptake inhibitor (SNRI) used in the treatment of fibromyalgia and depressive disorders. It helps reduce chronic widespread pain, improve mood, and enhance physical function in patients affected by central pain sensitization conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Milnacipran Hydrochloride 50 mg

Mechanism of Action

Milnacipran works by inhibiting the reuptake of two key neurotransmitters in the central nervous system: serotonin and norepinephrine. Its actions include:

• Increasing serotonin levels to improve mood and emotional stability
• Enhancing norepinephrine activity to improve pain modulation pathways
• Reducing central sensitization associated with chronic pain disorders
• Improving energy levels, motivation, and cognitive function

This dual mechanism makes it effective in both pain relief and mood improvement.

Indications

Milran Tablet is indicated for:

• Fibromyalgia syndrome
• Major depressive disorder (as prescribed by a physician)
• Chronic musculoskeletal pain associated with central sensitization
• Fatigue and functional impairment related to fibromyalgia

Dosage and Administration

• Dosage is individualized and should be determined by a physician
• Commonly taken once or twice daily
• Can be taken with or without food
• Start with a lower dose and gradually increase to reduce side effects
• Do not discontinue abruptly without medical supervision

Benefits

• Helps reduce chronic widespread pain
• Improves mood and emotional well-being
• Enhances physical function and daily activity levels
• Reduces fatigue associated with fibromyalgia
• Supports overall quality of life improvement

Possible Side Effects

Common side effects may include:

• Nausea
• Headache
• Dizziness
• Dry mouth
• Excessive sweating
• Insomnia or sleep disturbance

Less common but serious effects may include increased blood pressure or mood changes.

Precautions

• Use cautiously in patients with hypertension or heart disease
• Regular monitoring of blood pressure is recommended
• Not suitable for patients with severe renal impairment
• Avoid abrupt discontinuation to prevent withdrawal symptoms
• Use during pregnancy or breastfeeding only if clearly necessary

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Milnacipran may interact with:

• Other antidepressants (risk of serotonin syndrome)
• MAO inhibitors (contraindicated)
• Antihypertensive medications
• CNS stimulants

Always inform your healthcare provider about all ongoing medications.

Storage

• Store below 30°C in a cool, dry place
• Protect from moisture and direct light
• Keep out of reach of children.