Mobifen Suppository 50 mg contains Diclofenac Sodium, a potent non-steroidal anti-inflammatory drug (NSAID) designed to relieve moderate to severe pain and reduce inflammation. The rectal suppository formulation provides an effective alternative for patients who are unable to take oral medication due to nausea, vomiting, or gastrointestinal sensitivity. It is suitable for acute pain, post-operative discomfort, and inflammatory conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Diclofenac Sodium 50 mg

Mechanism of Action

Diclofenac Sodium works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for the production of prostaglandins. Prostaglandins mediate pain, inflammation, and fever. By reducing their synthesis, Mobifen Suppository alleviates pain, decreases inflammation, and improves patient comfort. Rectal administration ensures rapid absorption and effectiveness, especially in patients unable to tolerate oral NSAIDs.

Indications

Mobifen Suppository 50 mg is indicated for:

• Acute moderate to severe pain
• Musculoskeletal pain, including sprains and strains
• Post-operative pain management
• Pain due to inflammatory conditions
• Patients who cannot tolerate oral NSAID therapy

Dosage and Administration

• Adults: 1 suppository rectally 1–2 times daily, or as prescribed by a physician
• Insert gently into the rectum after cleaning the area
• Use the lowest effective dose for the shortest duration necessary
• Avoid exceeding the prescribed dose to reduce risk of side effects

Benefits

• Provides rapid and potent pain relief
• Reduces inflammation and swelling
• Convenient for patients unable to take oral medication
• Improves comfort and compliance in acute and post-operative pain
• Well-suited for short-term pain management

Side Effects

Common side effects:

• Mild rectal irritation or discomfort
• Nausea or abdominal upset
• Dizziness or headache

Serious side effects (rare):

• Gastrointestinal bleeding or ulceration
• Kidney or liver impairment
• Severe allergic reactions (rash, swelling, difficulty breathing)
• Cardiovascular risks with prolonged use

Precautions

• Use with caution in patients with gastrointestinal, kidney, or liver disorders
• Avoid prolonged use to minimize risk of serious side effects
• Monitor renal and liver function in patients on long-term therapy
• Elderly patients may be more sensitive to adverse effects
• Consult a physician if symptoms persist or worsen

Contraindications

• Hypersensitivity to Diclofenac or other NSAIDs
• Active gastrointestinal bleeding or ulceration
• Severe renal or hepatic impairment
• History of NSAID-induced asthma or hypersensitivity
• Late pregnancy (third trimester)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Diclofenac may interact with:

• Anticoagulants (e.g., warfarin) – increased risk of bleeding
• Other NSAIDs – increased risk of gastrointestinal side effects
• ACE inhibitors or diuretics – may affect kidney function
• Corticosteroids – increased risk of GI irritation and ulcers

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.