Ostan Plus Tablet 50 mg + 12.5 mg is a combination antihypertensive medication containing Losartan Potassium (50 mg) and Hydrochlorothiazide (12.5 mg). This dual-action formulation is designed to provide effective management of high blood pressure (hypertension) by targeting two key mechanisms that control blood pressure.

Losartan Potassium is an angiotensin II receptor blocker (ARB) that relaxes blood vessels, improving blood flow and reducing the heart's workload. Hydrochlorothiazide is a thiazide diuretic that helps the body eliminate excess salt and water through urine, which further lowers blood pressure and reduces fluid retention. Together, these agents provide a complementary approach to controlling hypertension and reducing cardiovascular risk.

Ostan Plus is often prescribed for patients whose blood pressure is not adequately controlled with a single antihypertensive agent. By combining two medications in one tablet, it enhances convenience, improves adherence, and ensures more consistent blood pressure control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Contains Losartan Potassium 50 mg + Hydrochlorothiazide 12.5 mg per tablet

• Combines ARB and diuretic for enhanced blood pressure control

• Reduces risk of stroke, heart attack, and heart failure

• Helps manage fluid retention and supports kidney protection

• Convenient once-daily oral tablet for improved patient compliance

• Suitable for adults with essential hypertension

Indications

Ostan Plus Tablet is primarily indicated for:

• Hypertension: To lower high blood pressure in adults, reducing the risk of cardiovascular complications

• Patients inadequately controlled on monotherapy: Effective for individuals not achieving target blood pressure with Losartan alone

• Fluid retention management: Helps manage mild edema associated with high blood pressure

This combination therapy is typically prescribed alongside lifestyle modifications, such as dietary sodium reduction, regular exercise, and weight management, to achieve optimal blood pressure control.

Mechanism of Action

• Losartan Potassium: Blocks angiotensin II receptors (AT1) in blood vessels, preventing vasoconstriction, lowering blood pressure, and reducing strain on the heart and kidneys.

• Hydrochlorothiazide: Increases the excretion of sodium and water by the kidneys, decreasing blood volume and further lowering blood pressure.

By targeting both vascular resistance and fluid retention, Ostan Plus provides a balanced and effective approach to controlling hypertension.

Dosage and Administration

• Usually administered once daily, with or without food

• Swallow tablets whole with water

• The exact dosage should be determined by a healthcare professional based on blood pressure response and patient condition

• Continue therapy as prescribed, even if blood pressure readings improve early

Possible Side Effects

Ostan Plus Tablet is generally well tolerated, but some patients may experience:

• Dizziness or lightheadedness

• Headache

• Fatigue

• Increased urination

• Mild gastrointestinal discomfort

• Rarely, electrolyte imbalances such as low potassium or sodium

Seek immediate medical attention if severe symptoms, allergic reactions, or signs of kidney or liver issues occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Not recommended during pregnancy, particularly in the second and third trimesters

• Use with caution in patients with kidney or liver impairment

• Regular monitoring of electrolytes and kidney function may be advised

• Inform your doctor of all other medications being taken, especially diuretics, NSAIDs, or other antihypertensives

Storage Instructions

• Store in a cool, dry place below 30°C

• Keep tablets in the original container, tightly closed

• Protect from moisture and sunlight

• Keep out of reach of children.